Results for ADAM8

General Information

Gene ID 101
Gene Symbol ADAM8
Gene Name ADAM metallopeptidase domain 8
Gene Type protein-coding
Cytoband 10q26.3
Ensembl ID ENSG00000151651
#miR regulators 2
Omim ID 602267
Gene ontology GO:0000902: cell morphogenesis
GO:0001525: angiogenesis
GO:0002523: leukocyte migration involved in inflammatory response
GO:0002675: positive regulation of acute inflammatory response
GO:0006508: proteolysis
GO:0006954: inflammatory response
GO:0010954: positive regulation of protein processing
GO:0016337: cell-cell adhesion
GO:0022407: regulation of cell-cell adhesion
GO:0033089: positive regulation of T cell differentiation in thymus
GO:0035419: activation of MAPK activity involved in innate immune response
GO:0043524: negative regulation of neuron apoptotic process
GO:0045780: positive regulation of bone resorption
GO:0045785: positive regulation of cell adhesion
GO:0048247: lymphocyte chemotaxis
GO:0050714: positive regulation of protein secretion
GO:0051044: positive regulation of membrane protein ectodomain proteolysis
GO:0051092: positive regulation of NF-kappaB transcription factor activity
GO:0051897: positive regulation of protein kinase B signaling cascade
GO:0070245: positive regulation of thymocyte apoptotic process
GO:0071456: cellular response to hypoxia
GO:2000309: positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
GO:2000391: positive regulation of neutrophil extravasation
GO:2000415: positive regulation of fibronectin-dependent thymocyte migration
GO:2000418: positive regulation of eosinophil migration
GO:0005886: plasma membrane
GO:0002102: podosome
GO:0005887: integral to plasma membrane
GO:0005737: cytoplasm
GO:0009986: cell surface
GO:0032010: phagolysosome
GO:0032127: dense core granule membrane
GO:0042581: specific granule
GO:0070820: tertiary granule
GO:0071065: alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
GO:0071133: alpha9-beta1 integrin-ADAM8 complex
GO:0005515: protein binding
GO:0005509: calcium ion binding
GO:0004222: metalloendopeptidase activity
GO:0008237: metallopeptidase activity
GO:0050839: cell adhesion molecule binding
GO:0008270: zinc ion binding
GO:0043621: protein self-association
KEGG pathways ---

PubMed abstracts associated with ADAM8

PMID Title Tumor Value
22215309 Upregulation of a disintegrin and metalloprotease 8 influences tumor metastasis and prognosis in patients with osteosarcoma. yes yes
title all all