Results for EDNRA

General Information

Gene ID 1909
Gene Symbol EDNRA
Gene Name endothelin receptor type A
Gene Type protein-coding
Cytoband 4q31.22
Ensembl ID ENSG00000151617
#miR regulators 8
Omim ID 131243
Gene ontology GO:0001569: patterning of blood vessels
GO:0001666: response to hypoxia
GO:0001701: in utero embryonic development
GO:0001821: histamine secretion
GO:0001934: positive regulation of protein phosphorylation
GO:0003094: glomerular filtration
GO:0007165: signal transduction
GO:0006939: smooth muscle contraction
GO:0007186: G-protein coupled receptor signaling pathway
GO:0007190: activation of adenylate cyclase activity
GO:0007202: activation of phospholipase C activity
GO:0007204: elevation of cytosolic calcium ion concentration
GO:0007205: protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007266: Rho protein signal transduction
GO:0007507: heart development
GO:0007568: aging
GO:0007585: respiratory gaseous exchange
GO:0043066: negative regulation of apoptotic process
GO:0008217: regulation of blood pressure
GO:0008283: cell proliferation
GO:0008284: positive regulation of cell proliferation
GO:0014032: neural crest cell development
GO:0014824: artery smooth muscle contraction
GO:0015758: glucose transport
GO:0019233: sensory perception of pain
GO:0071260: cellular response to mechanical stimulus
GO:0030818: negative regulation of cAMP biosynthetic process
GO:0032496: response to lipopolysaccharide
GO:0042310: vasoconstriction
GO:0042482: positive regulation of odontogenesis
GO:0043084: penile erection
GO:0043278: response to morphine
GO:0048144: fibroblast proliferation
GO:0048484: enteric nervous system development
GO:0048659: smooth muscle cell proliferation
GO:0050678: regulation of epithelial cell proliferation
GO:0050729: positive regulation of inflammatory response
GO:0051281: positive regulation of release of sequestered calcium ion into cytosol
GO:0051482: elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0060137: maternal process involved in parturition
GO:0060322: head development
GO:0070374: positive regulation of ERK1 and ERK2 cascade
GO:0090023: positive regulation of neutrophil chemotaxis
GO:0090184: positive regulation of kidney development
GO:0005886: plasma membrane
GO:0016020: membrane
GO:0005887: integral to plasma membrane
GO:0030315: T-tubule
GO:0031965: nuclear membrane
GO:0005515: protein binding
GO:0004435: phosphatidylinositol phospholipase C activity
GO:0004962: endothelin receptor activity
KEGG pathways 4020: Calcium signaling pathway
4080: Neuroactive ligand-receptor interaction
4270: Vascular smooth muscle contraction

PubMed abstracts associated with EDNRA

PMID Title Tumor Value
16417466 Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving the transcription factor NF-kappaB in human osteosarcoma. no no
22446894 Knockdown of endothelin A receptor expression inhibits osteosarcoma pulmonary metastasis in an orthotopic xenograft mouse model. no no
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