Results for ESR1

General Information

Gene ID 2099
Gene Symbol ESR1
Gene Name estrogen receptor 1
Gene Type protein-coding
Cytoband 6q25.1
Ensembl ID ENSG00000091831
#miR regulators 17
Omim ID 114480 133430 608446 615363
Gene ontology GO:0001547: antral ovarian follicle growth
GO:0002064: epithelial cell development
GO:0007165: signal transduction
GO:0006351: transcription, DNA-dependent
GO:0006355: regulation of transcription, DNA-dependent
GO:0006367: transcription initiation from RNA polymerase II promoter
GO:0007200: phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204: elevation of cytosolic calcium ion concentration
GO:0008209: androgen metabolic process
GO:0008584: male gonad development
GO:0010467: gene expression
GO:0010629: negative regulation of gene expression
GO:0010863: positive regulation of phospholipase C activity
GO:0042981: regulation of apoptotic process
GO:0030518: intracellular steroid hormone receptor signaling pathway
GO:0030520: intracellular estrogen receptor signaling pathway
GO:0032355: response to estradiol stimulus
GO:0043124: negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043627: response to estrogen stimulus
GO:0045429: positive regulation of nitric oxide biosynthetic process
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048146: positive regulation of fibroblast proliferation
GO:0048386: positive regulation of retinoic acid receptor signaling pathway
GO:0051000: positive regulation of nitric-oxide synthase activity
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060065: uterus development
GO:0060068: vagina development
GO:0060523: prostate epithelial cord elongation
GO:0060527: prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060687: regulation of branching involved in prostate gland morphogenesis
GO:0060745: mammary gland branching involved in pregnancy
GO:0060749: mammary gland alveolus development
GO:0060750: epithelial cell proliferation involved in mammary gland duct elongation
GO:0071392: cellular response to estradiol stimulus
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0016020: membrane
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0005794: Golgi apparatus
GO:0005515: protein binding
GO:0001046: core promoter sequence-specific DNA binding
GO:0003682: chromatin binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0003707: steroid hormone receptor activity
GO:0005496: steroid binding
GO:0008013: beta-catenin binding
GO:0008134: transcription factor binding
GO:0008270: zinc ion binding
GO:0042802: identical protein binding
GO:0019899: enzyme binding
GO:0030235: nitric-oxide synthase regulator activity
GO:0030284: estrogen receptor activity
GO:0034056: estrogen response element binding
GO:0038052: estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
KEGG pathways ---

PubMed abstracts associated with ESR1

PMID Title Tumor Value
6930152 Correlation between prognostic factors and blood variables in osteosarcoma. yes no
8033827 Cell cycle-dependent expression of estrogen receptor and effect of estrogen on proliferation of synchronized human osteoblast-like osteosarcoma cells. no no
8726395 Immunohistochemical localization of the estrogen receptor in human osteoblastic SaOS-2 cells: association of receptor levels with alkaline phosphatase activity. no no
10411143 Expression and regulation of the meprin beta gene in human cancer cells. no no
14528100 Analysis of polymorphisms of the vitamin D receptor, estrogen receptor, and collagen Ialpha1 genes and their relationship with height in children with bone cancer. yes no
19347870 Down-regulation of epidermal growth factor receptor induced by estrogens and phytoestrogens promotes the differentiation of U2OS human osteosarcoma cells. no no
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