Results for FHIT

General Information

Gene ID 2272
Gene Symbol FHIT
Gene Name fragile histidine triad
Gene Type protein-coding
Cytoband 3p14.2
Ensembl ID ENSG00000189283 ENSG00000262683
#miR regulators 1
Omim ID 601153
Gene ontology GO:0006260: DNA replication
GO:0006163: purine nucleotide metabolic process
GO:0006351: transcription, DNA-dependent
GO:0006355: regulation of transcription, DNA-dependent
GO:0009117: nucleotide metabolic process
GO:0032435: negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0072332: intrinsic apoptotic signaling pathway by p53 class mediator
GO:0005829: cytosol
GO:0005737: cytoplasm
GO:0043231: intracellular membrane-bounded organelle
GO:0000166: nucleotide binding
GO:0005515: protein binding
GO:0003824: catalytic activity
GO:0042802: identical protein binding
GO:0016787: hydrolase activity
GO:0031625: ubiquitin protein ligase binding
GO:0047710: bis(5'-adenosyl)-triphosphatase activity
KEGG pathways 230: Purine metabolism
5222: Small cell lung cancer
5223: Non-small cell lung cancer

PubMed abstracts associated with FHIT

PMID Title Tumor Value
9818023 Abnormalities of the FHIT transcripts in osteosarcoma and Ewing sarcoma. yes no
title all all