General Information
| Gene ID | 2272 |
|---|---|
| Gene Symbol | FHIT |
| Gene Name | fragile histidine triad |
| Gene Type | protein-coding |
| Cytoband | 3p14.2 |
| Ensembl ID | ENSG00000189283 ENSG00000262683 |
| #miR regulators | 1 |
| Omim ID | 601153 |
| Gene ontology |
GO:0006260: DNA replication GO:0006163: purine nucleotide metabolic process GO:0006351: transcription, DNA-dependent GO:0006355: regulation of transcription, DNA-dependent GO:0009117: nucleotide metabolic process GO:0032435: negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0072332: intrinsic apoptotic signaling pathway by p53 class mediator GO:0005829: cytosol GO:0005737: cytoplasm GO:0043231: intracellular membrane-bounded organelle GO:0000166: nucleotide binding GO:0005515: protein binding GO:0003824: catalytic activity GO:0042802: identical protein binding GO:0016787: hydrolase activity GO:0031625: ubiquitin protein ligase binding GO:0047710: bis(5'-adenosyl)-triphosphatase activity |
| KEGG pathways |
230: Purine metabolism 5222: Small cell lung cancer 5223: Non-small cell lung cancer |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 9818023 | Abnormalities of the FHIT transcripts in osteosarcoma and Ewing sarcoma. | yes | no |
| title | all | all |