General Information
Gene ID | 2274 |
---|---|
Gene Symbol | FHL2 |
Gene Name | four and a half LIM domains 2 |
Gene Type | protein-coding |
Cytoband | 2q12.2 |
Ensembl ID | ENSG00000115641 |
#miR regulators | 9 |
Omim ID | 602633 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001649: osteoblast differentiation GO:0006351: transcription, DNA-dependent GO:0043066: negative regulation of apoptotic process GO:0009725: response to hormone stimulus GO:0045893: positive regulation of transcription, DNA-dependent GO:0030521: androgen receptor signaling pathway GO:0044255: cellular lipid metabolic process GO:0044281: small molecule metabolic process GO:0055014: atrial cardiac muscle cell development GO:0055015: ventricular cardiac muscle cell development GO:0060347: heart trabecula formation GO:0005634: nucleus GO:0005654: nucleoplasm GO:0005925: focal adhesion GO:0015629: actin cytoskeleton GO:0030018: Z disc GO:0031430: M band GO:0005515: protein binding GO:0003713: transcription coactivator activity GO:0008134: transcription factor binding GO:0008270: zinc ion binding GO:0042802: identical protein binding GO:0050681: androgen receptor binding |
KEGG pathways |
4380: Osteoclast differentiation |
PMID | Title | Tumor | Value |
---|---|---|---|
23383046 | FHL2 silencing reduces Wnt signaling and osteosarcoma tumorigenesis in vitro and in vivo. | yes | no |
title | all | all |