Results for IFI16

General Information

Gene ID 3428
Gene Symbol IFI16
Gene Name interferon, gamma-inducible protein 16
Gene Type protein-coding
Cytoband 1q22
Ensembl ID ENSG00000163565
#miR regulators 2
Omim ID 147586
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001819: positive regulation of cytokine production
GO:0002218: activation of innate immune response
GO:0009615: response to virus
GO:0006351: transcription, DNA-dependent
GO:0006355: regulation of transcription, DNA-dependent
GO:0006914: autophagy
GO:0006954: inflammatory response
GO:0008283: cell proliferation
GO:0010506: regulation of autophagy
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0030097: hemopoiesis
GO:0030099: myeloid cell differentiation
GO:0030224: monocyte differentiation
GO:0032481: positive regulation of type I interferon production
GO:0032731: positive regulation of interleukin-1 beta production
GO:0042149: cellular response to glucose starvation
GO:0042771: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043392: negative regulation of DNA binding
GO:0045071: negative regulation of viral genome replication
GO:0045087: innate immune response
GO:0045824: negative regulation of innate immune response
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0051607: defense response to virus
GO:0071479: cellular response to ionizing radiation
GO:0072332: intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097202: activation of cysteine-type endopeptidase activity
GO:2000117: negative regulation of cysteine-type endopeptidase activity
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005730: nucleolus
GO:0016607: nuclear speck
GO:0005515: protein binding
GO:0003690: double-stranded DNA binding
GO:0008134: transcription factor binding
KEGG pathways ---

PubMed abstracts associated with IFI16

PMID Title Tumor Value
17569615 IFI16 inhibits tumorigenicity and cell proliferation of bone and cartilage tumor cells. no no
title all all