Results for IDO1

General Information

Gene ID 3620
Gene Symbol IDO1
Gene Name indoleamine 2,3-dioxygenase 1
Gene Type protein-coding
Cytoband 8p12-p11
Ensembl ID ENSG00000131203
#miR regulators 5
Omim ID 147435
Gene ontology GO:0002534: cytokine production involved in inflammatory response
GO:0002666: positive regulation of T cell tolerance induction
GO:0002678: positive regulation of chronic inflammatory response
GO:0002830: positive regulation of type 2 immune response
GO:0006569: tryptophan catabolic process
GO:0007565: female pregnancy
GO:0007610: behavior
GO:0019441: tryptophan catabolic process to kynurenine
GO:0032496: response to lipopolysaccharide
GO:0032693: negative regulation of interleukin-10 production
GO:0032735: positive regulation of interleukin-12 production
GO:0033555: multicellular organismal response to stress
GO:0034276: kynurenic acid biosynthetic process
GO:0034641: cellular nitrogen compound metabolic process
GO:0043065: positive regulation of apoptotic process
GO:0044281: small molecule metabolic process
GO:0046007: negative regulation of activated T cell proliferation
GO:0070233: negative regulation of T cell apoptotic process
GO:0005829: cytosol
GO:0030485: smooth muscle contractile fiber
GO:0032421: stereocilium bundle
GO:0009055: electron carrier activity
GO:0004833: tryptophan 2,3-dioxygenase activity
GO:0046872: metal ion binding
GO:0020037: heme binding
GO:0033754: indoleamine 2,3-dioxygenase activity
KEGG pathways 380: Tryptophan metabolism
1100: Metabolic pathways
5143: African trypanosomiasis

PubMed abstracts associated with IDO1

PMID Title Tumor Value
12014674 Interleukin-12 and interleukin-18 induce indoleamine 2,3-dioxygenase (IDO) activity in human osteosarcoma cell lines independently from interferon-gamma. no no
19802733 Prognostic value of indoleamine 2,3-dioxygenase expression in high grade osteosarcoma. yes yes
title all all