Results for ITGA4

General Information

Gene ID 3676
Gene Symbol ITGA4
Gene Name integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
Gene Type protein-coding
Cytoband 2q31.3
Ensembl ID ENSG00000115232
#miR regulators 5
Omim ID 192975
Gene ontology GO:0007157: heterophilic cell-cell adhesion
GO:0001974: blood vessel remodeling
GO:0007596: blood coagulation
GO:0007159: leukocyte cell-cell adhesion
GO:0007229: integrin-mediated signaling pathway
GO:0007507: heart development
GO:0030183: B cell differentiation
GO:0050776: regulation of immune response
GO:0050900: leukocyte migration
GO:0060324: face development
GO:0060710: chorio-allantoic fusion
GO:0005886: plasma membrane
GO:0008305: integrin complex
GO:0009897: external side of plasma membrane
GO:0009986: cell surface
GO:0070062: extracellular vesicular exosome
GO:0005515: protein binding
GO:0001968: fibronectin binding
GO:0046872: metal ion binding
KEGG pathways 4510: Focal adhesion
4512: ECM-receptor interaction
4514: Cell adhesion molecules (CAMs)
4640: Hematopoietic cell lineage
4670: Leukocyte transendothelial migration
4672: Intestinal immune network for IgA production
4810: Regulation of actin cytoskeleton
5140: Leishmaniasis
5410: Hypertrophic cardiomyopathy (HCM)
5412: Arrhythmogenic right ventricular cardiomyopathy (ARVC)
5414: Dilated cardiomyopathy

PubMed abstracts associated with ITGA4

PMID Title Tumor Value
1281143 VLA-4 integrin on sarcoma cell lines recognizes endothelial VCAM-1. Differential regulation of the VLA-4 avidity on various sarcoma cell lines. no no
12616540 Alpha 4 integrin increases anoikis of human osteosarcoma cells. yes no
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