General Information
| Gene ID | 5327 |
|---|---|
| Gene Symbol | PLAT |
| Gene Name | plasminogen activator, tissue |
| Gene Type | protein-coding |
| Cytoband | 8p12 |
| Ensembl ID | ENSG00000104368 |
| #miR regulators | 2 |
| Omim ID | 173370 612348 |
| Gene ontology |
GO:0001666: response to hypoxia GO:0007596: blood coagulation GO:0006464: cellular protein modification process GO:0006508: proteolysis GO:0014909: smooth muscle cell migration GO:0031639: plasminogen activation GO:0035249: synaptic transmission, glutamatergic GO:0042730: fibrinolysis GO:0043434: response to peptide hormone stimulus GO:0045861: negative regulation of proteolysis GO:0048008: platelet-derived growth factor receptor signaling pathway GO:0048167: regulation of synaptic plasticity GO:0051384: response to glucocorticoid stimulus GO:0051591: response to cAMP GO:0060279: positive regulation of ovulation GO:0005576: extracellular region GO:0005615: extracellular space GO:0005737: cytoplasm GO:0030141: secretory granule GO:0009986: cell surface GO:0045177: apical part of cell GO:0045202: synapse GO:0005515: protein binding GO:0004252: serine-type endopeptidase activity |
| KEGG pathways |
4610: Complement and coagulation cascades |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 1481722 | The effect of transforming growth factor beta on the plasminogen activator activity of normal human osteoblast-like cells and a human osteosarcoma cell line MG-63. | no | no |
| 1571831 | Effects of interleukin-1, tumor necrosis factor -beta, and forskolin on tissue plasminogen activator activity in human osteoblastic osteosarcoma cells. | no | no |
| 11713566 | Plasminogen activators and their inhibitor in bone tumors and tumor-like damages. | yes | no |
| title | all | all |