General Information
| Gene ID | 5829 |
|---|---|
| Gene Symbol | PXN |
| Gene Name | paxillin |
| Gene Type | protein-coding |
| Cytoband | 12q24.31 |
| Ensembl ID | ENSG00000089159 |
| #miR regulators | 3 |
| Omim ID | 602505 |
| Gene ontology |
GO:0000187: activation of MAPK activity GO:0006936: muscle contraction GO:0007010: cytoskeleton organization GO:0007155: cell adhesion GO:0007165: signal transduction GO:0006928: cellular component movement GO:0007172: signal complex assembly GO:0007173: epidermal growth factor receptor signaling pathway GO:0007229: integrin-mediated signaling pathway GO:0018108: peptidyl-tyrosine phosphorylation GO:0030032: lamellipodium assembly GO:0034329: cell junction assembly GO:0034614: cellular response to reactive oxygen species GO:0048041: focal adhesion assembly GO:0048754: branching morphogenesis of an epithelial tube GO:0060396: growth hormone receptor signaling pathway GO:0005886: plasma membrane GO:0005875: microtubule associated complex GO:0005925: focal adhesion GO:0005938: cell cortex GO:0030027: lamellipodium GO:0005515: protein binding GO:0005178: integrin binding GO:0008013: beta-catenin binding GO:0008270: zinc ion binding GO:0017166: vinculin binding GO:0019901: protein kinase binding GO:0051435: BH4 domain binding |
| KEGG pathways |
4062: Chemokine signaling pathway 4370: VEGF signaling pathway 4510: Focal adhesion 4670: Leukocyte transendothelial migration 4810: Regulation of actin cytoskeleton 5100: Bacterial invasion of epithelial cells |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 15870699 | Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma. | no | no |
| title | all | all |