General Information
Gene ID | 958 |
---|---|
Gene Symbol | CD40 |
Gene Name | CD40 molecule, TNF receptor superfamily member 5 |
Gene Type | protein-coding |
Cytoband | 20q12-q13.2 |
Ensembl ID | ENSG00000101017 |
#miR regulators | 10 |
Omim ID | 109535 606843 |
Gene ontology |
GO:0001934: positive regulation of protein phosphorylation GO:0002768: immune response-regulating cell surface receptor signaling pathway GO:0006461: protein complex assembly GO:0006874: cellular calcium ion homeostasis GO:0006954: inflammatory response GO:0071260: cellular response to mechanical stimulus GO:0030168: platelet activation GO:0030890: positive regulation of B cell proliferation GO:0032735: positive regulation of interleukin-12 production GO:0032855: positive regulation of Rac GTPase activity GO:0042100: B cell proliferation GO:0042511: positive regulation of tyrosine phosphorylation of Stat1 protein GO:0043089: positive regulation of Cdc42 GTPase activity GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043406: positive regulation of MAP kinase activity GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048304: positive regulation of isotype switching to IgG isotypes GO:0050776: regulation of immune response GO:0051023: regulation of immunoglobulin secretion GO:0051092: positive regulation of NF-kappaB transcription factor activity GO:0051607: defense response to virus GO:0090037: positive regulation of protein kinase C signaling cascade GO:2000353: positive regulation of endothelial cell apoptotic process GO:0005886: plasma membrane GO:0005576: extracellular region GO:0005887: integral to plasma membrane GO:0043231: intracellular membrane-bounded organelle GO:0009897: external side of plasma membrane GO:0035631: CD40 receptor complex GO:0005515: protein binding GO:0004871: signal transducer activity GO:0004872: receptor activity GO:0019899: enzyme binding GO:0031625: ubiquitin protein ligase binding |
KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4514: Cell adhesion molecules (CAMs) 4620: Toll-like receptor signaling pathway 4672: Intestinal immune network for IgA production 5144: Malaria 5145: Toxoplasmosis 5310: Asthma 5320: Autoimmune thyroid disease 5322: Systemic lupus erythematosus 5330: Allograft rejection 5340: Primary immunodeficiency 5416: Viral myocarditis |
PMID | Title | Tumor | Value |
---|---|---|---|
9717810 | Expression of functional CD40 on human osteosarcoma and Ewing's sarcoma cells. | no | no |
title | all | all |