Results for CD40LG

General Information

Gene ID 959
Gene Symbol CD40LG
Gene Name CD40 ligand
Gene Type protein-coding
Cytoband Xq26
Ensembl ID ENSG00000102245
#miR regulators 3
Omim ID 300386 308230
Gene ontology GO:0006954: inflammatory response
GO:0007159: leukocyte cell-cell adhesion
GO:0043066: negative regulation of apoptotic process
GO:0030168: platelet activation
GO:0030183: B cell differentiation
GO:0032735: positive regulation of interleukin-12 production
GO:0042100: B cell proliferation
GO:0045190: isotype switching
GO:0048305: immunoglobulin secretion
GO:0050776: regulation of immune response
GO:0051023: regulation of immunoglobulin secretion
GO:2000353: positive regulation of endothelial cell apoptotic process
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0005887: integral to plasma membrane
GO:0005615: extracellular space
GO:0009897: external side of plasma membrane
GO:0005125: cytokine activity
GO:0005164: tumor necrosis factor receptor binding
GO:0005174: CD40 receptor binding
KEGG pathways 4060: Cytokine-cytokine receptor interaction
4514: Cell adhesion molecules (CAMs)
4660: T cell receptor signaling pathway
4672: Intestinal immune network for IgA production
5144: Malaria
5145: Toxoplasmosis
5310: Asthma
5320: Autoimmune thyroid disease
5322: Systemic lupus erythematosus
5330: Allograft rejection
5340: Primary immunodeficiency
5416: Viral myocarditis

PubMed abstracts associated with CD40LG

PMID Title Tumor Value
9717810 Expression of functional CD40 on human osteosarcoma and Ewing's sarcoma cells. no no
12621691 Serum concentrations of sCD30 and sCD40L in patients with malignant bone tumours. yes yes
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