General Information
| Gene ID | 959 |
|---|---|
| Gene Symbol | CD40LG |
| Gene Name | CD40 ligand |
| Gene Type | protein-coding |
| Cytoband | Xq26 |
| Ensembl ID | ENSG00000102245 |
| #miR regulators | 3 |
| Omim ID | 300386 308230 |
| Gene ontology |
GO:0006954: inflammatory response GO:0007159: leukocyte cell-cell adhesion GO:0043066: negative regulation of apoptotic process GO:0030168: platelet activation GO:0030183: B cell differentiation GO:0032735: positive regulation of interleukin-12 production GO:0042100: B cell proliferation GO:0045190: isotype switching GO:0048305: immunoglobulin secretion GO:0050776: regulation of immune response GO:0051023: regulation of immunoglobulin secretion GO:2000353: positive regulation of endothelial cell apoptotic process GO:0005886: plasma membrane GO:0016021: integral to membrane GO:0005887: integral to plasma membrane GO:0005615: extracellular space GO:0009897: external side of plasma membrane GO:0005125: cytokine activity GO:0005164: tumor necrosis factor receptor binding GO:0005174: CD40 receptor binding |
| KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4514: Cell adhesion molecules (CAMs) 4660: T cell receptor signaling pathway 4672: Intestinal immune network for IgA production 5144: Malaria 5145: Toxoplasmosis 5310: Asthma 5320: Autoimmune thyroid disease 5322: Systemic lupus erythematosus 5330: Allograft rejection 5340: Primary immunodeficiency 5416: Viral myocarditis |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 9717810 | Expression of functional CD40 on human osteosarcoma and Ewing's sarcoma cells. | no | no |
| 12621691 | Serum concentrations of sCD30 and sCD40L in patients with malignant bone tumours. | yes | yes |
| title | all | all |