Results for CD44

General Information

Gene ID 960
Gene Symbol CD44
Gene Name CD44 molecule (Indian blood group)
Gene Type protein-coding
Cytoband 11p13
Ensembl ID ENSG00000026508
#miR regulators 8
Omim ID 107269 609027
Gene ontology GO:0001658: branching involved in ureteric bud morphogenesis
GO:0002246: wound healing involved in inflammatory response
GO:0016055: Wnt receptor signaling pathway
GO:0005975: carbohydrate metabolic process
GO:0007160: cell-matrix adhesion
GO:0043066: negative regulation of apoptotic process
GO:0010628: positive regulation of gene expression
GO:0016337: cell-cell adhesion
GO:0019221: cytokine-mediated signaling pathway
GO:0030198: extracellular matrix organization
GO:0030203: glycosaminoglycan metabolic process
GO:0030212: hyaluronan metabolic process
GO:0030214: hyaluronan catabolic process
GO:0033138: positive regulation of peptidyl-serine phosphorylation
GO:0034116: positive regulation of heterotypic cell-cell adhesion
GO:0043154: negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043518: negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044281: small molecule metabolic process
GO:0044344: cellular response to fibroblast growth factor stimulus
GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation
GO:0051216: cartilage development
GO:0060333: interferon-gamma-mediated signaling pathway
GO:0060442: branching involved in prostate gland morphogenesis
GO:0070374: positive regulation of ERK1 and ERK2 cascade
GO:0070487: monocyte aggregation
GO:1900625: positive regulation of monocyte aggregation
GO:1902166: negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0005886: plasma membrane
GO:0005887: integral to plasma membrane
GO:0009897: external side of plasma membrane
GO:0009986: cell surface
GO:0016323: basolateral plasma membrane
GO:0005515: protein binding
GO:0004415: hyalurononglucosaminidase activity
GO:0004888: transmembrane signaling receptor activity
GO:0005518: collagen binding
GO:0005540: hyaluronic acid binding
KEGG pathways 4512: ECM-receptor interaction
4640: Hematopoietic cell lineage
5131: Shigellosis

PubMed abstracts associated with CD44

PMID Title Tumor Value
10541973 Expression of CD44 variants in osteosarcoma. yes yes
11746520 Cellular and molecular properties associated with osteosarcoma cells. yes no
11859242 Expression of CD44 isoforms correlates with the metastatic potential of osteosarcoma. yes yes
16773198 HAS3-related hyaluronan enhances biological activities necessary for metastasis of osteosarcoma cells. no no
16798617 Hypoxia and ionizing radiation: changes in adhesive properties and cell adhesion molecule expression in MG-63 three-dimensional tumor spheroids. no no
17786474 Ezrin and alpha-smooth muscle actin are immunohistochemical prognostic markers in conventional osteosarcomas. yes yes
19331807 Expression of Ezrin correlates with lung metastasis in Chinese patients with osteosarcoma. yes no
20562647 Immunoexpression of Ezrin and CD44 in patients with osteosarcoma. yes no
20855150 Small interfering RNA-directed knockdown of S100A4 decreases proliferation and invasiveness of osteosarcoma cells. no no
21801875 Podoplanin is regulated by AP-1 and promotes platelet aggregation and cell migration in osteosarcoma. yes no
22870217 Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma. no no
23031740 Li-Fraumeni syndrome with simultaneous osteosarcoma and liver cancer: increased expression of a CD44 variant isoform after chemotherapy. yes no
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