General Information
| Gene ID | 3090 |
|---|---|
| Gene Symbol | HIC1 |
| Gene Name | hypermethylated in cancer 1 |
| Gene Type | protein-coding |
| Cytoband | 17p13.3 |
| Ensembl ID | ENSG00000177374 |
| #miR regulators | 5 |
| Omim ID | 603825 |
| Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0016055: Wnt receptor signaling pathway GO:0006351: transcription, DNA-dependent GO:0006355: regulation of transcription, DNA-dependent GO:0007275: multicellular organismal development GO:0008630: intrinsic apoptotic signaling pathway in response to DNA damage GO:0030178: negative regulation of Wnt receptor signaling pathway GO:0043517: positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0000785: chromatin GO:0005634: nucleus GO:0005737: cytoplasm GO:0005515: protein binding GO:0003677: DNA binding GO:0003700: sequence-specific DNA binding transcription factor activity GO:0046872: metal ion binding GO:0042826: histone deacetylase binding GO:0043565: sequence-specific DNA binding |
| KEGG pathways | --- |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 15488761 | Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis. | yes | no |
| title | all | all |