General Information
| Gene ID | 54464 |
|---|---|
| Gene Symbol | XRN1 |
| Gene Name | 5'-3' exoribonuclease 1 |
| Gene Type | protein-coding |
| Cytoband | 3q23 |
| Ensembl ID | ENSG00000114127 |
| #miR regulators | 19 |
| Omim ID | 607994 |
| Gene ontology |
GO:0000288: nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000956: nuclear-transcribed mRNA catabolic process GO:0010467: gene expression GO:0016070: RNA metabolic process GO:0016071: mRNA metabolic process GO:0016075: rRNA catabolic process GO:0043928: exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay GO:0071028: nuclear mRNA surveillance GO:0071044: histone mRNA catabolic process GO:0005886: plasma membrane GO:0000932: cytoplasmic mRNA processing body GO:0005829: cytosol GO:0005737: cytoplasm GO:0005794: Golgi apparatus GO:0045111: intermediate filament cytoskeleton GO:0005515: protein binding GO:0003677: DNA binding GO:0003723: RNA binding GO:0008409: 5'-3' exonuclease activity |
| KEGG pathways |
3008: Ribosome biogenesis in eukaryotes 3018: RNA degradation |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 12426100 | The human homolog of yeast SEP1 is a novel candidate tumor suppressor gene in osteogenic sarcoma. | yes | no |
| 17234543 | Low-grade central osteosarcoma of the mandible: a case study report. | yes | no |
| 18019405 | Altered expression of cell cycle regulatory proteins in benign and malignant bone and soft tissue neoplasms. | yes | no |
| title | all | all |
