General Information
| Gene ID | 648 |
|---|---|
| Gene Symbol | BMI1 |
| Gene Name | BMI1 polycomb ring finger oncogene |
| Gene Type | protein-coding |
| Cytoband | 10p11.23 |
| Ensembl ID | ENSG00000168283 ENSG00000269897 |
| #miR regulators | 7 |
| Omim ID | 164831 |
| Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0006351: transcription, DNA-dependent GO:0007379: segment specification GO:0010468: regulation of gene expression GO:0016568: chromatin modification GO:0030097: hemopoiesis GO:0048146: positive regulation of fibroblast proliferation GO:0051443: positive regulation of ubiquitin-protein ligase activity GO:0000151: ubiquitin ligase complex GO:0005634: nucleus GO:0005737: cytoplasm GO:0005730: nucleolus GO:0031519: PcG protein complex GO:0035102: PRC1 complex GO:0005515: protein binding GO:0008270: zinc ion binding GO:0071535: RING-like zinc finger domain binding |
| KEGG pathways | --- |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 18332870 | Cisplatin treatment increases survival and expansion of a highly tumorigenic side-population fraction by upregulating VEGF/Flt1 autocrine signaling. | no | no |
| 20127006 | The knock-down of overexpressed EZH2 and BMI-1 does not prevent osteosarcoma growth. | yes | no |
| 21311599 | Overexpression of BMI-1 promotes cell growth and resistance to cisplatin treatment in osteosarcoma. | yes | no |
| title | all | all |