General Information
| Gene ID | 9401 |
|---|---|
| Gene Symbol | RECQL4 |
| Gene Name | RecQ protein-like 4 |
| Gene Type | protein-coding |
| Cytoband | 8q24.3 |
| Ensembl ID | ENSG00000160957 |
| #miR regulators | 2 |
| Omim ID | 218600 266280 268400 603780 |
| Gene ontology |
GO:0006260: DNA replication GO:0000733: DNA strand renaturation GO:0006281: DNA repair GO:0006310: DNA recombination GO:0007275: multicellular organismal development GO:0032508: DNA duplex unwinding GO:0005634: nucleus GO:0005737: cytoplasm GO:0000405: bubble DNA binding GO:0005524: ATP binding GO:0008270: zinc ion binding GO:0043140: ATP-dependent 3'-5' DNA helicase activity |
| KEGG pathways | --- |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 12734318 | Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome. | yes | yes |
| 15221963 | Mutation analysis of the RECQL4 gene in sporadic osteosarcomas. | yes | no |
| 19242607 | Recurrent RECQL4 imbalance and increased gene expression levels are associated with structural chromosomal instability in sporadic osteosarcoma. | yes | no |
| 20465837 | Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy. | yes | yes |
| title | all | all |