Results for CDH2

General Information

Gene ID 1000
Gene Symbol CDH2
Gene Name cadherin 2, type 1, N-cadherin (neuronal)
Gene Type protein-coding
Cytoband 18q11.2
Ensembl ID ENSG00000170558
#miR regulators 5
Omim ID 114020
Gene ontology GO:0007157: heterophilic cell-cell adhesion
GO:0007155: cell adhesion
GO:0007156: homophilic cell adhesion
GO:0016339: calcium-dependent cell-cell adhesion
GO:0016477: cell migration
GO:0034329: cell junction assembly
GO:0034332: adherens junction organization
GO:0042692: muscle cell differentiation
GO:0043410: positive regulation of MAPK cascade
GO:0045216: cell-cell junction organization
GO:0048514: blood vessel morphogenesis
GO:0051146: striated muscle cell differentiation
GO:0051149: positive regulation of muscle cell differentiation
GO:0090090: negative regulation of canonical Wnt receptor signaling pathway
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0005911: cell-cell junction
GO:0005913: cell-cell adherens junction
GO:0005916: fascia adherens
GO:0014704: intercalated disc
GO:0016324: apical plasma membrane
GO:0016342: catenin complex
GO:0030027: lamellipodium
GO:0045202: synapse
GO:0005509: calcium ion binding
GO:0008013: beta-catenin binding
GO:0019903: protein phosphatase binding
GO:0045294: alpha-catenin binding
GO:0045295: gamma-catenin binding
KEGG pathways 4514: Cell adhesion molecules (CAMs)
5412: Arrhythmogenic right ventricular cardiomyopathy (ARVC)

PubMed abstracts associated with CDH2

PMID Title Tumor Value
10550312 Anomalous cadherin expression in osteosarcoma. Possible relationships to metastasis and morphogenesis. yes yes
15670817 Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells. no no
17318900 Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells. no no
title all all