Results for HDAC6

General Information

Gene ID 10013
Gene Symbol HDAC6
Gene Name histone deacetylase 6
Gene Type protein-coding
Cytoband Xp11.23
Ensembl ID ENSG00000094631 ENSG00000269101
#miR regulators 1
Omim ID 300272
Gene ontology GO:0000209: protein polyubiquitination
GO:0006351: transcription, DNA-dependent
GO:0006476: protein deacetylation
GO:0006515: misfolded or incompletely synthesized protein catabolic process
GO:0006886: intracellular protein transport
GO:0007026: negative regulation of microtubule depolymerization
GO:0009636: response to toxic substance
GO:0009967: positive regulation of signal transduction
GO:0010033: response to organic substance
GO:0010469: regulation of receptor activity
GO:0010634: positive regulation of epithelial cell migration
GO:0010727: negative regulation of hydrogen peroxide metabolic process
GO:0010870: positive regulation of receptor biosynthetic process
GO:0016236: macroautophagy
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0016575: histone deacetylation
GO:0032418: lysosome localization
GO:0034983: peptidyl-lysine deacetylation
GO:0035967: cellular response to topologically incorrect protein
GO:0043162: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043241: protein complex disassembly
GO:0043242: negative regulation of protein complex disassembly
GO:0045861: negative regulation of proteolysis
GO:0051354: negative regulation of oxidoreductase activity
GO:0051788: response to misfolded protein
GO:0070848: response to growth factor stimulus
GO:0060632: regulation of microtubule-based movement
GO:0060765: regulation of androgen receptor signaling pathway
GO:0070201: regulation of establishment of protein localization
GO:0070301: cellular response to hydrogen peroxide
GO:0070842: aggresome assembly
GO:0070845: polyubiquitinated misfolded protein transport
GO:0070846: Hsp90 deacetylation
GO:0071218: cellular response to misfolded protein
GO:0090035: positive regulation of chaperone-mediated protein complex assembly
GO:0090042: tubulin deacetylation
GO:1901300: positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0000118: histone deacetylase complex
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005874: microtubule
GO:0005875: microtubule associated complex
GO:0005881: cytoplasmic microtubule
GO:0005901: caveola
GO:0016234: inclusion body
GO:0016235: aggresome
GO:0030286: dynein complex
GO:0031252: cell leading edge
GO:0048471: perinuclear region of cytoplasm
GO:0005515: protein binding
GO:0003779: actin binding
GO:0004407: histone deacetylase activity
GO:0008013: beta-catenin binding
GO:0008017: microtubule binding
GO:0008270: zinc ion binding
GO:0051879: Hsp90 protein binding
GO:0019899: enzyme binding
GO:0031593: polyubiquitin binding
GO:0032041: NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0042826: histone deacetylase binding
GO:0042903: tubulin deacetylase activity
GO:0043014: alpha-tubulin binding
GO:0046969: NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970: NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0048156: tau protein binding
GO:0048487: beta-tubulin binding
GO:0070840: dynein complex binding
GO:0097372: NAD-dependent histone deacetylase activity (H3-K18 specific)
KEGG pathways ---

PubMed abstracts associated with HDAC6

PMID Title Tumor Value
20181727 A mutation in the 3'-UTR of the HDAC6 gene abolishing the post-transcriptional regulation mediated by hsa-miR-433 is linked to a new form of dominant X-linked chondrodysplasia. no no
title all all