General Information
Gene ID | 10018 |
---|---|
Gene Symbol | BCL2L11 |
Gene Name | BCL2-like 11 (apoptosis facilitator) |
Gene Type | protein-coding |
Cytoband | 2q13 |
Ensembl ID | ENSG00000153094 |
#miR regulators | 25 |
Omim ID | 603827 |
Gene ontology |
GO:0001701: in utero embryonic development GO:0001782: B cell homeostasis GO:0001783: B cell apoptotic process GO:0001822: kidney development GO:0002262: myeloid cell homeostasis GO:0006915: apoptotic process GO:0006919: activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0007160: cell-matrix adhesion GO:0007283: spermatogenesis GO:0007420: brain development GO:0008584: male gonad development GO:0008630: intrinsic apoptotic signaling pathway in response to DNA damage GO:0030879: mammary gland development GO:0032464: positive regulation of protein homooligomerization GO:0034976: response to endoplasmic reticulum stress GO:0035148: tube formation GO:0042475: odontogenesis of dentin-containing tooth GO:0043029: T cell homeostasis GO:0043065: positive regulation of apoptotic process GO:0043525: positive regulation of neuron apoptotic process GO:0043583: ear development GO:0045787: positive regulation of cell cycle GO:0046620: regulation of organ growth GO:0048011: neurotrophin TRK receptor signaling pathway GO:0048066: developmental pigmentation GO:0048070: regulation of developmental pigmentation GO:0048536: spleen development GO:0048538: thymus development GO:0048563: post-embryonic organ morphogenesis GO:0060154: cellular process regulating host cell cycle in response to virus GO:0090200: positive regulation of release of cytochrome c from mitochondria GO:0097190: apoptotic signaling pathway GO:0097193: intrinsic apoptotic signaling pathway GO:1900740: positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:2000271: positive regulation of fibroblast apoptotic process GO:2001244: positive regulation of intrinsic apoptotic signaling pathway GO:0019898: extrinsic to membrane GO:0005829: cytosol GO:0005741: mitochondrial outer membrane GO:0005874: microtubule GO:0012505: endomembrane system GO:0097140: BIM-BCL-xl complex GO:0097141: BIM-BCL-2 complex GO:0005515: protein binding GO:0008017: microtubule binding GO:0046982: protein heterodimerization activity |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
20580954 | Functional and biological analysis of Bcl-xL expression in human osteosarcoma. | yes | no |
21490307 | The cyclin-dependent kinase inhibitor SCH 727965 (dinacliclib) induces the apoptosis of osteosarcoma cells. | no | no |
23266503 | Effects of baicalein on apoptosis, cell cycle arrest, migration and invasion of osteosarcoma cells. | no | no |
title | all | all |