Results for MICA

General Information

Gene ID 100507436
Gene Symbol MICA
Gene Name MHC class I polypeptide-related sequence A
Gene Type protein-coding
Cytoband 6p21.33
Ensembl ID ENSG00000204520 ENSG00000231225 ENSG00000235233 ENSG00000183214 ENSG00000233051
#miR regulators 7
Omim ID 600169
Gene ontology GO:0001913: T cell mediated cytotoxicity
GO:0002418: immune response to tumor cell
GO:0042742: defense response to bacterium
GO:0006974: response to DNA damage stimulus
GO:0042267: natural killer cell mediated cytotoxicity
GO:0019835: cytolysis
GO:0009408: response to heat
GO:0019048: modulation by virus of host morphology or physiology
GO:0019882: antigen processing and presentation
GO:0046629: gamma-delta T cell activation
GO:0051607: defense response to virus
GO:0005887: integral to plasma membrane
GO:0005615: extracellular space
GO:0005737: cytoplasm
GO:0009986: cell surface
GO:0046703: natural killer cell lectin-like receptor binding
KEGG pathways ---

PubMed abstracts associated with MICA

PMID Title Tumor Value
18348660 Prevalent expression of MHC class I chain-related molecule A in human osteosarcoma. yes no
22923031 Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells. no no
22992985 Hypoxia downregulates the expression of cell surface MICA without increasing soluble MICA in osteosarcoma cells in a HIF-1?-dependent manner. no no
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