Results for CDK6

General Information

Gene ID 1021
Gene Symbol CDK6
Gene Name cyclin-dependent kinase 6
Gene Type protein-coding
Cytoband 7q21-q22
Ensembl ID ENSG00000105810
#miR regulators 7
Omim ID 603368
Gene ontology GO:0000080: G1 phase of mitotic cell cycle
GO:0000082: G1/S transition of mitotic cell cycle
GO:0000278: mitotic cell cycle
GO:0001954: positive regulation of cell-matrix adhesion
GO:0003323: type B pancreatic cell development
GO:0009615: response to virus
GO:0006468: protein phosphorylation
GO:0007050: cell cycle arrest
GO:0008285: negative regulation of cell proliferation
GO:0010468: regulation of gene expression
GO:0014002: astrocyte development
GO:0021542: dentate gyrus development
GO:0021670: lateral ventricle development
GO:0042063: gliogenesis
GO:0043697: cell dedifferentiation
GO:0045596: negative regulation of cell differentiation
GO:0045638: negative regulation of myeloid cell differentiation
GO:0045646: regulation of erythrocyte differentiation
GO:0045668: negative regulation of osteoblast differentiation
GO:0045786: negative regulation of cell cycle
GO:0048146: positive regulation of fibroblast proliferation
GO:0048699: generation of neurons
GO:0050680: negative regulation of epithelial cell proliferation
GO:0051301: cell division
GO:2000145: regulation of cell motility
GO:2000773: negative regulation of cellular senescence
GO:0000307: cyclin-dependent protein kinase holoenzyme complex
GO:0001726: ruffle
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005515: protein binding
GO:0004693: cyclin-dependent protein serine/threonine kinase activity
GO:0005524: ATP binding
GO:0030332: cyclin binding
KEGG pathways 4110: Cell cycle
4115: p53 signaling pathway
5200: Pathways in cancer
5212: Pancreatic cancer
5214: Glioma
5218: Melanoma
5220: Chronic myeloid leukemia
5222: Small cell lung cancer
5223: Non-small cell lung cancer

PubMed abstracts associated with CDK6

PMID Title Tumor Value
9154817 Glucocorticoid receptor-mediated cell cycle arrest is achieved through distinct cell-specific transcriptional regulatory mechanisms. no no
24009496 How MicroRNA and Transcription Factor Co-regulatory Networks Affect Osteosarcoma Cell Proliferation no no
title all all