Results for SPRY2

General Information

Gene ID 10253
Gene Symbol SPRY2
Gene Name sprouty homolog 2 (Drosophila)
Gene Type protein-coding
Cytoband 13q31.1
Ensembl ID ENSG00000136158
#miR regulators 3
Omim ID 602466
Gene ontology GO:0007173: epidermal growth factor receptor signaling pathway
GO:0007605: sensory perception of sound
GO:0043066: negative regulation of apoptotic process
GO:0008285: negative regulation of cell proliferation
GO:0008543: fibroblast growth factor receptor signaling pathway
GO:0010628: positive regulation of gene expression
GO:0010801: negative regulation of peptidyl-threonine phosphorylation
GO:0033138: positive regulation of peptidyl-serine phosphorylation
GO:0034261: negative regulation of Ras GTPase activity
GO:0040037: negative regulation of fibroblast growth factor receptor signaling pathway
GO:0042059: negative regulation of epidermal growth factor receptor signaling pathway
GO:0042472: inner ear morphogenesis
GO:0043407: negative regulation of MAP kinase activity
GO:0045165: cell fate commitment
GO:0046580: negative regulation of Ras protein signal transduction
GO:0048754: branching morphogenesis of an epithelial tube
GO:0051387: negative regulation of neurotrophin TRK receptor signaling pathway
GO:0051897: positive regulation of protein kinase B signaling cascade
GO:0060425: lung morphogenesis
GO:0060437: lung growth
GO:0070373: negative regulation of ERK1 and ERK2 cascade
GO:0070374: positive regulation of ERK1 and ERK2 cascade
GO:0071902: positive regulation of protein serine/threonine kinase activity
GO:0005886: plasma membrane
GO:0005829: cytosol
GO:0005874: microtubule
GO:0032587: ruffle membrane
GO:0005515: protein binding
GO:0019901: protein kinase binding
GO:0030291: protein serine/threonine kinase inhibitor activity
GO:0043539: protein serine/threonine kinase activator activity
KEGG pathways 4630: Jak-STAT signaling pathway

PubMed abstracts associated with SPRY2

PMID Title Tumor Value
23831057 Sprouty2 but not Sprouty4 is a potent inhibitor of cell proliferation and migration of osteosarcoma cells. no no
title all all