General Information
Gene ID | 11035 |
---|---|
Gene Symbol | RIPK3 |
Gene Name | receptor-interacting serine-threonine kinase 3 |
Gene Type | protein-coding |
Cytoband | 14q11.2 |
Ensembl ID | ENSG00000129465 |
#miR regulators | 1 |
Omim ID | 605817 |
Gene ontology |
GO:0002224: toll-like receptor signaling pathway GO:0002756: MyD88-independent toll-like receptor signaling pathway GO:0007165: signal transduction GO:0006464: cellular protein modification process GO:0007249: I-kappaB kinase/NF-kappaB cascade GO:0032147: activation of protein kinase activity GO:0032481: positive regulation of type I interferon production GO:0034138: toll-like receptor 3 signaling pathway GO:0034142: toll-like receptor 4 signaling pathway GO:0035666: TRIF-dependent toll-like receptor signaling pathway GO:0051260: protein homooligomerization GO:0045087: innate immune response GO:0051092: positive regulation of NF-kappaB transcription factor activity GO:0051291: protein heterooligomerization GO:0060545: positive regulation of necroptosis GO:0097190: apoptotic signaling pathway GO:0005886: plasma membrane GO:0005739: mitochondrion GO:0005829: cytosol GO:0005515: protein binding GO:0003713: transcription coactivator activity GO:0004672: protein kinase activity GO:0004674: protein serine/threonine kinase activity GO:0004704: NF-kappaB-inducing kinase activity GO:0005524: ATP binding GO:0042802: identical protein binding |
KEGG pathways |
4623: Cytosolic DNA-sensing pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
22057483 | RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT. | no | no |
title | all | all |