General Information
| Gene ID | 11186 |
|---|---|
| Gene Symbol | RASSF1 |
| Gene Name | Ras association (RalGDS/AF-6) domain family member 1 |
| Gene Type | protein-coding |
| Cytoband | 3p21.3 |
| Ensembl ID | ENSG00000068028 ENSG00000263005 |
| #miR regulators | 4 |
| Omim ID | 211980 605082 |
| Gene ontology |
GO:0006974: response to DNA damage stimulus GO:0007050: cell cycle arrest GO:0007265: Ras protein signal transduction GO:0050821: protein stabilization GO:0031398: positive regulation of protein ubiquitination GO:0071157: negative regulation of cell cycle arrest GO:0005886: plasma membrane GO:0000922: spindle pole GO:0005634: nucleus GO:0005737: cytoplasm GO:0005815: microtubule organizing center GO:0005874: microtubule GO:0015630: microtubule cytoskeleton GO:0005515: protein binding GO:0008270: zinc ion binding GO:0042802: identical protein binding GO:0047485: protein N-terminus binding |
| KEGG pathways |
5200: Pathways in cancer 5219: Bladder cancer 5223: Non-small cell lung cancer |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 12792742 | Inactivation of the RASSF1A in osteosarcoma. | yes | no |
| 16007340 | Ras-association domain family 1 protein, RASSF1C, is an IGFBP-5 binding partner and a potential regulator of osteoblast cell proliferation. | no | no |
| 16502411 | Quantitative analysis of promoter hypermethylation in multiple genes in osteosarcoma. | yes | yes |
| title | all | all |