Results for CHUK

General Information

Gene ID 1147
Gene Symbol CHUK
Gene Name conserved helix-loop-helix ubiquitous kinase
Gene Type protein-coding
Cytoband 10q24-q25
Ensembl ID ENSG00000213341
#miR regulators 11
Omim ID 600664 613630
Gene ontology GO:0002011: morphogenesis of an epithelial sheet
GO:0002224: toll-like receptor signaling pathway
GO:0002755: MyD88-dependent toll-like receptor signaling pathway
GO:0002756: MyD88-independent toll-like receptor signaling pathway
GO:0003009: skeletal muscle contraction
GO:0009615: response to virus
GO:0006468: protein phosphorylation
GO:0006954: inflammatory response
GO:0006955: immune response
GO:0007173: epidermal growth factor receptor signaling pathway
GO:0007249: I-kappaB kinase/NF-kappaB cascade
GO:0007252: I-kappaB phosphorylation
GO:0007266: Rho protein signal transduction
GO:0009653: anatomical structure morphogenesis
GO:0007595: lactation
GO:0008543: fibroblast growth factor receptor signaling pathway
GO:0042493: response to drug
GO:0009636: response to toxic substance
GO:0048015: phosphatidylinositol-mediated signaling
GO:0050852: T cell receptor signaling pathway
GO:0030316: osteoclast differentiation
GO:0032481: positive regulation of type I interferon production
GO:0032496: response to lipopolysaccharide
GO:0033194: response to hydroperoxide
GO:0033598: mammary gland epithelial cell proliferation
GO:0034134: toll-like receptor 2 signaling pathway
GO:0034138: toll-like receptor 3 signaling pathway
GO:0034142: toll-like receptor 4 signaling pathway
GO:0034146: toll-like receptor 5 signaling pathway
GO:0034162: toll-like receptor 9 signaling pathway
GO:0034166: toll-like receptor 10 signaling pathway
GO:0035666: TRIF-dependent toll-like receptor signaling pathway
GO:0035872: nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0038123: toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124: toll-like receptor TLR6:TLR2 signaling pathway
GO:0042475: odontogenesis of dentin-containing tooth
GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043200: response to amino acid stimulus
GO:0045087: innate immune response
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0051092: positive regulation of NF-kappaB transcription factor activity
GO:0051146: striated muscle cell differentiation
GO:0060749: mammary gland alveolus development
GO:0070423: nucleotide-binding oligomerization domain containing signaling pathway
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0043231: intracellular membrane-bounded organelle
GO:0008385: IkappaB kinase complex
GO:0009898: internal side of plasma membrane
GO:0035631: CD40 receptor complex
GO:0005515: protein binding
GO:0004672: protein kinase activity
GO:0005524: ATP binding
GO:0008384: IkappaB kinase activity
GO:0042802: identical protein binding
GO:0046982: protein heterodimerization activity
KEGG pathways 4010: MAPK signaling pathway
4062: Chemokine signaling pathway
4210: Apoptosis
4380: Osteoclast differentiation
4620: Toll-like receptor signaling pathway
4621: NOD-like receptor signaling pathway
4622: RIG-I-like receptor signaling pathway
4623: Cytosolic DNA-sensing pathway
4660: T cell receptor signaling pathway
4662: B cell receptor signaling pathway
4920: Adipocytokine signaling pathway
5120: Epithelial cell signaling in Helicobacter pylori infection
5131: Shigellosis
5142: Chagas disease (American trypanosomiasis)
5145: Toxoplasmosis
5160: Hepatitis C
5200: Pathways in cancer
5212: Pancreatic cancer
5215: Prostate cancer
5220: Chronic myeloid leukemia
5221: Acute myeloid leukemia
5222: Small cell lung cancer

PubMed abstracts associated with CHUK

PMID Title Tumor Value
16797629 Green tea polyphenols-induced apoptosis in human osteosarcoma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB. no no
19496172 Stromal cell-derived factor-1/CXCR4 enhanced motility of human osteosarcoma cells involves MEK1/2, ERK and NF-kappaB-dependent pathways. no no
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