General Information
| Gene ID | 121340 |
|---|---|
| Gene Symbol | SP7 |
| Gene Name | Sp7 transcription factor |
| Gene Type | protein-coding |
| Cytoband | 12q13.13 |
| Ensembl ID | ENSG00000170374 |
| #miR regulators | 3 |
| Omim ID | 606633 613849 |
| Gene ontology |
GO:0001649: osteoblast differentiation GO:0006351: transcription, DNA-dependent GO:0006357: regulation of transcription from RNA polymerase II promoter GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0060218: hematopoietic stem cell differentiation GO:2000738: positive regulation of stem cell differentiation GO:0005634: nucleus GO:0005737: cytoplasm GO:0003677: DNA binding GO:0046872: metal ion binding GO:0017151: DEAD/H-box RNA helicase binding |
| KEGG pathways | --- |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 16734381 | Sp1 family of transcription factors regulates the human alpha2 (XI) collagen gene (COL11A2) in Saos-2 osteoblastic cells. | no | no |
| 18838962 | Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects. | no | no |
| 19228774 | Notch signaling contributes to the pathogenesis of human osteosarcomas. | no | no |
| 23262982 | Preventing MEK1 activation influences the responses of human osteosarcoma cells to bone morphogenetic proteins 2 and 9. | no | no |
| 23827457 | MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31. | no | no |
| title | all | all |