Results for CCR5

General Information

Gene ID 1234
Gene Symbol CCR5
Gene Name chemokine (C-C motif) receptor 5 (gene/pseudogene)
Gene Type protein-coding
Cytoband 3p21.31
Ensembl ID ENSG00000160791
#miR regulators 10
Omim ID 601373 609532 610379 612522
Gene ontology GO:0000165: MAPK cascade
GO:0002407: dendritic cell chemotaxis
GO:0006816: calcium ion transport
GO:0006935: chemotaxis
GO:0006954: inflammatory response
GO:0006955: immune response
GO:0006968: cellular defense response
GO:0007166: cell surface receptor signaling pathway
GO:0007186: G-protein coupled receptor signaling pathway
GO:0007204: elevation of cytosolic calcium ion concentration
GO:0019722: calcium-mediated signaling
GO:0007267: cell-cell signaling
GO:0016032: viral process
GO:0014808: release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0019048: modulation by virus of host morphology or physiology
GO:0023052: signaling
GO:0030260: entry into host cell
GO:0070098: chemokine-mediated signaling pathway
GO:0070723: response to cholesterol
GO:0071222: cellular response to lipopolysaccharide
GO:0005886: plasma membrane
GO:0005887: integral to plasma membrane
GO:0005737: cytoplasm
GO:0005768: endosome
GO:0009897: external side of plasma membrane
GO:0009986: cell surface
GO:0005515: protein binding
GO:0003779: actin binding
GO:0004435: phosphatidylinositol phospholipase C activity
GO:0004950: chemokine receptor activity
GO:0015026: coreceptor activity
GO:0016493: C-C chemokine receptor activity
GO:0019957: C-C chemokine binding
GO:0071791: chemokine (C-C motif) ligand 5 binding
KEGG pathways 4060: Cytokine-cytokine receptor interaction
4062: Chemokine signaling pathway
4144: Endocytosis
5145: Toxoplasmosis

PubMed abstracts associated with CCR5

PMID Title Tumor Value
18215331 A complex pattern of chemokine receptor expression is seen in osteosarcoma. yes yes
22506069 CCL5 and CCR5 interaction promotes cell motility in human osteosarcoma. no no
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