Results for CREBBP

General Information

Gene ID 1387
Gene Symbol CREBBP
Gene Name CREB binding protein
Gene Type protein-coding
Cytoband 16p13.3
Ensembl ID ENSG00000005339
#miR regulators 4
Omim ID 180849 600140
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001666: response to hypoxia
GO:0007165: signal transduction
GO:0006355: regulation of transcription, DNA-dependent
GO:0006367: transcription initiation from RNA polymerase II promoter
GO:0006461: protein complex assembly
GO:0007219: Notch signaling pathway
GO:0008589: regulation of smoothened signaling pathway
GO:0010467: gene expression
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0016573: histone acetylation
GO:0018076: N-terminal peptidyl-lysine acetylation
GO:0019048: modulation by virus of host morphology or physiology
GO:0030718: germ-line stem cell maintenance
GO:0032481: positive regulation of type I interferon production
GO:0042592: homeostatic process
GO:0042733: embryonic digit morphogenesis
GO:0044255: cellular lipid metabolic process
GO:0044281: small molecule metabolic process
GO:0045087: innate immune response
GO:0061418: regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456: cellular response to hypoxia
GO:0000123: histone acetyltransferase complex
GO:0000790: nuclear chromatin
GO:0000940: condensed chromosome outer kinetochore
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005667: transcription factor complex
GO:0016604: nuclear body
GO:0005515: protein binding
GO:0000987: core promoter proximal region sequence-specific DNA binding
GO:0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001085: RNA polymerase II transcription factor binding
GO:0001102: RNA polymerase II activating transcription factor binding
GO:0001105: RNA polymerase II transcription coactivator activity
GO:0001191: RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0002039: p53 binding
GO:0003682: chromatin binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0003713: transcription coactivator activity
GO:0004402: histone acetyltransferase activity
GO:0004871: signal transducer activity
GO:0008134: transcription factor binding
GO:0008270: zinc ion binding
GO:0016407: acetyltransferase activity
GO:0043426: MRF binding
KEGG pathways 4110: Cell cycle
4310: Wnt signaling pathway
4330: Notch signaling pathway
4350: TGF-beta signaling pathway
4520: Adherens junction
4630: Jak-STAT signaling pathway
4720: Long-term potentiation
4916: Melanogenesis
5016: Huntington's disease
5200: Pathways in cancer
5211: Renal cell carcinoma
5215: Prostate cancer

PubMed abstracts associated with CREBBP

PMID Title Tumor Value
16734381 Sp1 family of transcription factors regulates the human alpha2 (XI) collagen gene (COL11A2) in Saos-2 osteoblastic cells. no no
16878156 Cooperation between Myc and YY1 provides novel silencing transcriptional targets of alpha3beta1-integrin in tumour cells. no no
title all all