General Information
Gene ID | 1436 |
---|---|
Gene Symbol | CSF1R |
Gene Name | colony stimulating factor 1 receptor |
Gene Type | protein-coding |
Cytoband | 5q32 |
Ensembl ID | ENSG00000182578 |
#miR regulators | 5 |
Omim ID | 164770 221820 |
Gene ontology |
GO:0001934: positive regulation of protein phosphorylation GO:0007165: signal transduction GO:0007169: transmembrane receptor protein tyrosine kinase signaling pathway GO:0006954: inflammatory response GO:0007275: multicellular organismal development GO:0008283: cell proliferation GO:0008284: positive regulation of cell proliferation GO:0008360: regulation of cell shape GO:0018108: peptidyl-tyrosine phosphorylation GO:0019221: cytokine-mediated signaling pathway GO:0048015: phosphatidylinositol-mediated signaling GO:0030097: hemopoiesis GO:0030224: monocyte differentiation GO:0030225: macrophage differentiation GO:0030316: osteoclast differentiation GO:0030335: positive regulation of cell migration GO:0031529: ruffle organization GO:0036006: cellular response to macrophage colony-stimulating factor stimulus GO:0042517: positive regulation of tyrosine phosphorylation of Stat3 protein GO:0045087: innate immune response GO:0045124: regulation of bone resorption GO:0045217: cell-cell junction maintenance GO:0046488: phosphatidylinositol metabolic process GO:0046777: protein autophosphorylation GO:0060603: mammary gland duct morphogenesis GO:0061098: positive regulation of protein tyrosine kinase activity GO:0070374: positive regulation of ERK1 and ERK2 cascade GO:0071345: cellular response to cytokine stimulus GO:0071902: positive regulation of protein serine/threonine kinase activity GO:0090197: positive regulation of chemokine secretion GO:2000147: positive regulation of cell motility GO:2000249: regulation of actin cytoskeleton reorganization GO:0005886: plasma membrane GO:0005887: integral to plasma membrane GO:0009986: cell surface GO:0043235: receptor complex GO:0005011: macrophage colony-stimulating factor receptor activity GO:0005524: ATP binding GO:0019955: cytokine binding GO:0042803: protein homodimerization activity |
KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4144: Endocytosis 4380: Osteoclast differentiation 4640: Hematopoietic cell lineage 5200: Pathways in cancer |
PMID | Title | Tumor | Value |
---|---|---|---|
20225287 | Bone deposition, bone resorption, and osteosarcoma. | yes | yes |
title | all | all |