General Information
Gene ID | 1437 |
---|---|
Gene Symbol | CSF2 |
Gene Name | colony stimulating factor 2 (granulocyte-macrophage) |
Gene Type | protein-coding |
Cytoband | 5q31.1 |
Ensembl ID | ENSG00000164400 |
#miR regulators | 3 |
Omim ID | 138960 |
Gene ontology |
GO:0001892: embryonic placenta development GO:0006955: immune response GO:0008284: positive regulation of cell proliferation GO:0010628: positive regulation of gene expression GO:0010744: positive regulation of macrophage derived foam cell differentiation GO:0032747: positive regulation of interleukin-23 production GO:0042045: epithelial fluid transport GO:0042116: macrophage activation GO:0042523: positive regulation of tyrosine phosphorylation of Stat5 protein GO:0043011: myeloid dendritic cell differentiation GO:0045740: positive regulation of DNA replication GO:0045918: negative regulation of cytolysis GO:0071222: cellular response to lipopolysaccharide GO:0071803: positive regulation of podosome assembly GO:0097028: dendritic cell differentiation GO:2001240: negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:0005576: extracellular region GO:0005615: extracellular space GO:0005515: protein binding GO:0005125: cytokine activity GO:0005129: granulocyte macrophage colony-stimulating factor receptor binding GO:0008083: growth factor activity |
KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4630: Jak-STAT signaling pathway 4640: Hematopoietic cell lineage 4650: Natural killer cell mediated cytotoxicity 4660: T cell receptor signaling pathway 4664: Fc epsilon RI signaling pathway 5146: Amoebiasis 5323: Rheumatoid arthritis |
PMID | Title | Tumor | Value |
---|---|---|---|
2069168 | The effect of rhGM-CSF on the proliferation of osteogenic sarcoma cells. | no | no |
3057504 | Human granulocyte-macrophage colony-stimulating factor is a growth factor active on a variety of cell types of nonhemopoietic origin. | no | no |
12232677 | Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces the osteoblastic differentiation of the human osteosarcoma cell line SaOS-2. | no | no |
14706926 | Effect of human granulocyte macrophage-colony stimulating factor on differentiation and apoptosis of the human osteosarcoma cell line SaOS-2. | no | no |
title | all | all |