Results for CTLA4

General Information

Gene ID 1493
Gene Symbol CTLA4
Gene Name cytotoxic T-lymphocyte-associated protein 4
Gene Type protein-coding
Cytoband 2q33
Ensembl ID ENSG00000163599
#miR regulators 5
Omim ID 123890 140300 601388 609755
Gene ontology GO:0006955: immune response
GO:0006974: response to DNA damage stimulus
GO:0030889: negative regulation of B cell proliferation
GO:0031295: T cell costimulation
GO:0043065: positive regulation of apoptotic process
GO:0045590: negative regulation of regulatory T cell differentiation
GO:0050853: B cell receptor signaling pathway
GO:0005886: plasma membrane
GO:0005887: integral to plasma membrane
GO:0005794: Golgi apparatus
GO:0009897: external side of plasma membrane
GO:0045334: clathrin-coated endocytic vesicle
GO:0048471: perinuclear region of cytoplasm
GO:0005515: protein binding
KEGG pathways 4514: Cell adhesion molecules (CAMs)
4660: T cell receptor signaling pathway
5320: Autoimmune thyroid disease
5323: Rheumatoid arthritis

PubMed abstracts associated with CTLA4

PMID Title Tumor Value
15912538 CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction. yes no
21453059 Cytotoxic T-lymphocyte antigen-4 +49G/A polymorphism is associated with increased risk of osteosarcoma. yes yes
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