General Information
| Gene ID | 1508 |
|---|---|
| Gene Symbol | CTSB |
| Gene Name | cathepsin B |
| Gene Type | protein-coding |
| Cytoband | 8p22 |
| Ensembl ID | ENSG00000164733 |
| #miR regulators | 8 |
| Omim ID | 116810 |
| Gene ontology |
GO:0002224: toll-like receptor signaling pathway GO:0006508: proteolysis GO:0042981: regulation of apoptotic process GO:0022617: extracellular matrix disassembly GO:0030198: extracellular matrix organization GO:0030574: collagen catabolic process GO:0045087: innate immune response GO:0050790: regulation of catalytic activity GO:0097067: cellular response to thyroid hormone stimulus GO:0005622: intracellular GO:0005764: lysosome GO:0005739: mitochondrion GO:0005576: extracellular region GO:0005615: extracellular space GO:0005730: nucleolus GO:0043231: intracellular membrane-bounded organelle GO:0036021: endolysosome lumen GO:0042470: melanosome GO:0048471: perinuclear region of cytoplasm GO:0005515: protein binding GO:0004197: cysteine-type endopeptidase activity GO:0008234: cysteine-type peptidase activity GO:0008233: peptidase activity |
| KEGG pathways |
4142: Lysosome 4612: Antigen processing and presentation |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 10086509 | Protease expression in dedifferentiated parosteal osteosarcoma. | yes | no |
| 10606250 | Inhibitory effects of antisense cathepsin B cDNA transfection on invasion and motility in a human osteosarcoma cell line. | no | no |
| 18598236 | Up-regulation of cathepsin B expression and enhanced secretion in mitochondrial DNA-depleted osteosarcoma cells. | no | no |
| title | all | all |