General Information
| Gene ID | 1513 |
|---|---|
| Gene Symbol | CTSK |
| Gene Name | cathepsin K |
| Gene Type | protein-coding |
| Cytoband | 1q21 |
| Ensembl ID | ENSG00000143387 |
| #miR regulators | 15 |
| Omim ID | 265800 601105 |
| Gene ontology |
GO:0001957: intramembranous ossification GO:0002224: toll-like receptor signaling pathway GO:0006508: proteolysis GO:0022617: extracellular matrix disassembly GO:0030198: extracellular matrix organization GO:0030574: collagen catabolic process GO:0045087: innate immune response GO:0045453: bone resorption GO:0005576: extracellular region GO:0005615: extracellular space GO:0036021: endolysosome lumen GO:0004197: cysteine-type endopeptidase activity GO:0008234: cysteine-type peptidase activity |
| KEGG pathways |
4142: Lysosome 4380: Osteoclast differentiation 4620: Toll-like receptor signaling pathway 5323: Rheumatoid arthritis |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 17683065 | Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis. | yes | yes |
| 19020756 | Increased osteoclast activity is associated with aggressiveness of osteosarcoma. | yes | no |
| title | all | all |