Results for CTSL1

General Information

Gene ID 1514
Gene Symbol CTSL1
Gene Name cathepsin L1
Gene Type protein-coding
Cytoband 9q21.33
Ensembl ID ENSG00000135047
#miR regulators 1
Omim ID 116880
Gene ontology GO:0002224: toll-like receptor signaling pathway
GO:0002250: adaptive immune response
GO:0006508: proteolysis
GO:0019882: antigen processing and presentation
GO:0019886: antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0022617: extracellular matrix disassembly
GO:0030198: extracellular matrix organization
GO:0030574: collagen catabolic process
GO:0045087: innate immune response
GO:0071888: macrophage apoptotic process
GO:0097067: cellular response to thyroid hormone stimulus
GO:0005764: lysosome
GO:0005576: extracellular region
GO:0005634: nucleus
GO:0036021: endolysosome lumen
GO:0043202: lysosomal lumen
GO:0005515: protein binding
GO:0004197: cysteine-type endopeptidase activity
GO:0042393: histone binding
GO:0008234: cysteine-type peptidase activity
KEGG pathways 4142: Lysosome
4145: Phagosome
4612: Antigen processing and presentation
5323: Rheumatoid arthritis

PubMed abstracts associated with CTSL1

PMID Title Tumor Value
8835762 Enhanced expression of cathepsin L in metastatic bone tumors. yes no
11498774 Cathepsin L antisense oligonucleotides in a human osteosarcoma cell line: effects on the invasive phenotype. no no
17683065 Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis. yes yes
title all all