Results for CYP27B1

General Information

Gene ID 1594
Gene Symbol CYP27B1
Gene Name cytochrome P450, family 27, subfamily B, polypeptide 1
Gene Type protein-coding
Cytoband 12q13.1-q13.3
Ensembl ID ENSG00000111012
#miR regulators 10
Omim ID 264700 609506
Gene ontology GO:0006766: vitamin metabolic process
GO:0006805: xenobiotic metabolic process
GO:0006816: calcium ion transport
GO:0008202: steroid metabolic process
GO:0008285: negative regulation of cell proliferation
GO:0010956: negative regulation of calcidiol 1-monooxygenase activity
GO:0010980: positive regulation of vitamin D 24-hydroxylase activity
GO:0030282: bone mineralization
GO:0030308: negative regulation of cell growth
GO:0030500: regulation of bone mineralization
GO:0032496: response to lipopolysaccharide
GO:0033280: response to vitamin D
GO:0034341: response to interferon-gamma
GO:0036378: calcitriol biosynthetic process from calciol
GO:0042359: vitamin D metabolic process
GO:0042369: vitamin D catabolic process
GO:0043627: response to estrogen stimulus
GO:0044281: small molecule metabolic process
GO:0045618: positive regulation of keratinocyte differentiation
GO:0046697: decidualization
GO:0055074: calcium ion homeostasis
GO:0070314: G1 to G0 transition
GO:0070564: positive regulation of vitamin D receptor signaling pathway
GO:0005739: mitochondrion
GO:0005737: cytoplasm
GO:0005741: mitochondrial outer membrane
GO:0009055: electron carrier activity
GO:0004498: calcidiol 1-monooxygenase activity
GO:0005506: iron ion binding
GO:0020037: heme binding
KEGG pathways 100: Steroid biosynthesis
1100: Metabolic pathways

PubMed abstracts associated with CYP27B1

PMID Title Tumor Value
15540165 Gene amplifications in osteosarcoma-CGH microarray analysis. yes no
17254772 RNAi-mediated silencing of CYP27B1 abolishes 1,25(OH)2D3 synthesis and reduces osteocalcin and CYP24 mRNA expression in human osteosarcoma (HOS) cells. no no
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