Results for DCC

General Information

Gene ID 1630
Gene Symbol DCC
Gene Name deleted in colorectal carcinoma
Gene Type protein-coding
Cytoband 18q21.3
Ensembl ID ENSG00000187323
#miR regulators 16
Omim ID 114500 120470 157600
Gene ontology GO:0001764: neuron migration
GO:0001975: response to amphetamine
GO:0006915: apoptotic process
GO:0007409: axonogenesis
GO:0007411: axon guidance
GO:0010976: positive regulation of neuron projection development
GO:0010977: negative regulation of neuron projection development
GO:0042981: regulation of apoptotic process
GO:0021965: spinal cord ventral commissure morphogenesis
GO:0033563: dorsal/ventral axon guidance
GO:0033564: anterior/posterior axon guidance
GO:0043065: positive regulation of apoptotic process
GO:0048671: negative regulation of collateral sprouting
GO:0070374: positive regulation of ERK1 and ERK2 cascade
GO:2000171: negative regulation of dendrite development
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0005829: cytosol
GO:0030424: axon
GO:0032584: growth cone membrane
GO:0045121: membrane raft
GO:0005515: protein binding
GO:0003713: transcription coactivator activity
GO:0004888: transmembrane signaling receptor activity
GO:0005042: netrin receptor activity
GO:0042802: identical protein binding
KEGG pathways 4360: Axon guidance
5200: Pathways in cancer
5210: Colorectal cancer

PubMed abstracts associated with DCC

PMID Title Tumor Value
9155051 Frequent reduction or loss of DCC gene expression in human osteosarcoma. yes no
title all all