Results for GADD45A

General Information

Gene ID 1647
Gene Symbol GADD45A
Gene Name growth arrest and DNA-damage-inducible, alpha
Gene Type protein-coding
Cytoband 1p31.2
Ensembl ID ENSG00000116717
#miR regulators 5
Omim ID 126335
Gene ontology GO:0000079: regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006915: apoptotic process
GO:0006281: DNA repair
GO:0006469: negative regulation of protein kinase activity
GO:0007050: cell cycle arrest
GO:0007098: centrosome cycle
GO:2000379: positive regulation of reactive oxygen species metabolic process
GO:0071260: cellular response to mechanical stimulus
GO:0042770: signal transduction in response to DNA damage
GO:0071479: cellular response to ionizing radiation
GO:0005634: nucleus
GO:0005515: protein binding
GO:0001047: core promoter binding
KEGG pathways 4010: MAPK signaling pathway
4110: Cell cycle
4115: p53 signaling pathway

PubMed abstracts associated with GADD45A

PMID Title Tumor Value
18097539 Apoptotic genes as potential markers of metastatic phenotype in human osteosarcoma cell lines. no no
18472964 Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells. no no
19052873 Multidrug resistant osteosarcoma cell lines exhibit deficiency of GADD45alpha expression. no no
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