Results for E2F4

General Information

Gene ID 1874
Gene Symbol E2F4
Gene Name E2F transcription factor 4, p107/p130-binding
Gene Type protein-coding
Cytoband 16q21-q22
Ensembl ID ENSG00000205250
#miR regulators 1
Omim ID 600659
Gene ontology GO:0000083: regulation of transcription involved in G1/S phase of mitotic cell cycle
GO:0000278: mitotic cell cycle
GO:0002064: epithelial cell development
GO:0006351: transcription, DNA-dependent
GO:0006367: transcription initiation from RNA polymerase II promoter
GO:0006884: cell volume homeostasis
GO:0007179: transforming growth factor beta receptor signaling pathway
GO:0009887: organ morphogenesis
GO:0008015: blood circulation
GO:0008361: regulation of cell size
GO:0042384: cilium assembly
GO:0010467: gene expression
GO:0042127: regulation of cell proliferation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0005654: nucleoplasm
GO:0005667: transcription factor complex
GO:0005515: protein binding
GO:0003677: DNA binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0008134: transcription factor binding
GO:0019904: protein domain specific binding
KEGG pathways 4110: Cell cycle
4350: TGF-beta signaling pathway

PubMed abstracts associated with E2F4

PMID Title Tumor Value
11707342 Identification of twenty-two candidate markers for human osteogenic sarcoma. no no
12789260 Triggering of p73-dependent apoptosis in osteosarcoma is under the control of E2Fs-pRb2/p130 complexes. no no
12813132 mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma. yes yes
24009496 How MicroRNA and Transcription Factor Co-regulatory Networks Affect Osteosarcoma Cell Proliferation no no
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