Results for EDNRB

General Information

Gene ID 1910
Gene Symbol EDNRB
Gene Name endothelin receptor type B
Gene Type protein-coding
Cytoband 13q22
Ensembl ID ENSG00000136160
#miR regulators 12
Omim ID 131244 277580 600155 600501
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001755: neural crest cell migration
GO:0001934: positive regulation of protein phosphorylation
GO:0035815: positive regulation of renal sodium excretion
GO:0035810: positive regulation of urine volume
GO:0006885: regulation of pH
GO:0007166: cell surface receptor signaling pathway
GO:0007194: negative regulation of adenylate cyclase activity
GO:0007200: phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204: elevation of cytosolic calcium ion concentration
GO:0007399: nervous system development
GO:0007422: peripheral nervous system development
GO:0007497: posterior midgut development
GO:0007568: aging
GO:0043066: negative regulation of apoptotic process
GO:0008217: regulation of blood pressure
GO:0008284: positive regulation of cell proliferation
GO:0014043: negative regulation of neuron maturation
GO:0014070: response to organic cyclic compound
GO:0014826: vein smooth muscle contraction
GO:0019233: sensory perception of pain
GO:0019934: cGMP-mediated signaling
GO:0030318: melanocyte differentiation
GO:0032269: negative regulation of cellular protein metabolic process
GO:0035645: enteric smooth muscle cell differentiation
GO:0042045: epithelial fluid transport
GO:0042310: vasoconstriction
GO:0042311: vasodilation
GO:0048246: macrophage chemotaxis
GO:0048265: response to pain
GO:0048484: enteric nervous system development
GO:0050678: regulation of epithelial cell proliferation
GO:0051930: regulation of sensory perception of pain
GO:0060406: positive regulation of penile erection
GO:0071222: cellular response to lipopolysaccharide
GO:0086100: endothelin receptor signaling pathway
GO:0005886: plasma membrane
GO:0005887: integral to plasma membrane
GO:0031965: nuclear membrane
GO:0045121: membrane raft
GO:0005515: protein binding
GO:0004962: endothelin receptor activity
GO:0017046: peptide hormone binding
GO:0031702: type 1 angiotensin receptor binding
KEGG pathways 4020: Calcium signaling pathway
4080: Neuroactive ligand-receptor interaction
4916: Melanogenesis

PubMed abstracts associated with EDNRB

PMID Title Tumor Value
16417466 Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving the transcription factor NF-kappaB in human osteosarcoma. no no
title all all