General Information
| Gene ID | 1942 |
|---|---|
| Gene Symbol | EFNA1 |
| Gene Name | ephrin-A1 |
| Gene Type | protein-coding |
| Cytoband | 1q21-q22 |
| Ensembl ID | ENSG00000169242 |
| #miR regulators | 6 |
| Omim ID | 191164 |
| Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0000187: activation of MAPK activity GO:0001525: angiogenesis GO:0003180: aortic valve morphogenesis GO:0003183: mitral valve morphogenesis GO:0003199: endocardial cushion to mesenchymal transition involved in heart valve formation GO:0007267: cell-cell signaling GO:0010719: negative regulation of epithelial to mesenchymal transition GO:0014028: notochord formation GO:0016477: cell migration GO:0030182: neuron differentiation GO:0033628: regulation of cell adhesion mediated by integrin GO:0034446: substrate adhesion-dependent cell spreading GO:0043535: regulation of blood vessel endothelial cell migration GO:0045765: regulation of angiogenesis GO:0048013: ephrin receptor signaling pathway GO:0050730: regulation of peptidyl-tyrosine phosphorylation GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation GO:0050770: regulation of axonogenesis GO:0061002: negative regulation of dendritic spine morphogenesis GO:0005576: extracellular region GO:0046658: anchored to plasma membrane GO:0005887: integral to plasma membrane GO:0005515: protein binding GO:0005102: receptor binding GO:0046875: ephrin receptor binding |
| KEGG pathways |
4360: Axon guidance |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 12209731 | Human osteosarcoma expresses specific ephrin profiles: implications for tumorigenicity and prognosis. | yes | yes |
| 21166698 | De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway. | no | no |
| title | all | all |