Results for EFNA1

General Information

Gene ID 1942
Gene Symbol EFNA1
Gene Name ephrin-A1
Gene Type protein-coding
Cytoband 1q21-q22
Ensembl ID ENSG00000169242
#miR regulators 6
Omim ID 191164
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0000187: activation of MAPK activity
GO:0001525: angiogenesis
GO:0003180: aortic valve morphogenesis
GO:0003183: mitral valve morphogenesis
GO:0003199: endocardial cushion to mesenchymal transition involved in heart valve formation
GO:0007267: cell-cell signaling
GO:0010719: negative regulation of epithelial to mesenchymal transition
GO:0014028: notochord formation
GO:0016477: cell migration
GO:0030182: neuron differentiation
GO:0033628: regulation of cell adhesion mediated by integrin
GO:0034446: substrate adhesion-dependent cell spreading
GO:0043535: regulation of blood vessel endothelial cell migration
GO:0045765: regulation of angiogenesis
GO:0048013: ephrin receptor signaling pathway
GO:0050730: regulation of peptidyl-tyrosine phosphorylation
GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation
GO:0050770: regulation of axonogenesis
GO:0061002: negative regulation of dendritic spine morphogenesis
GO:0005576: extracellular region
GO:0046658: anchored to plasma membrane
GO:0005887: integral to plasma membrane
GO:0005515: protein binding
GO:0005102: receptor binding
GO:0046875: ephrin receptor binding
KEGG pathways 4360: Axon guidance

PubMed abstracts associated with EFNA1

PMID Title Tumor Value
12209731 Human osteosarcoma expresses specific ephrin profiles: implications for tumorigenicity and prognosis. yes yes
21166698 De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway. no no
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