Results for EGR1

General Information

Gene ID 1958
Gene Symbol EGR1
Gene Name early growth response 1
Gene Type protein-coding
Cytoband 5q31.1
Ensembl ID ENSG00000120738
#miR regulators 10
Omim ID 128990
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001975: response to amphetamine
GO:0006366: transcription from RNA polymerase II promoter
GO:0007611: learning or memory
GO:0007623: circadian rhythm
GO:0009749: response to glucose stimulus
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0019221: cytokine-mediated signaling pathway
GO:0071260: cellular response to mechanical stimulus
GO:0030217: T cell differentiation
GO:0030509: BMP signaling pathway
GO:0031667: response to nutrient levels
GO:0032869: cellular response to insulin stimulus
GO:0033233: regulation of protein sumoylation
GO:0034465: response to carbon monoxide
GO:0035690: cellular response to drug
GO:0035914: skeletal muscle cell differentiation
GO:0042220: response to cocaine
GO:0043525: positive regulation of neuron apoptotic process
GO:0045471: response to ethanol
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048169: regulation of long-term neuronal synaptic plasticity
GO:0048709: oligodendrocyte differentiation
GO:0051602: response to electrical stimulus
GO:0060291: long-term synaptic potentiation
GO:0060337: type I interferon-mediated signaling pathway
GO:0070498: interleukin-1-mediated signaling pathway
GO:0071236: cellular response to antibiotic
GO:0071317: cellular response to isoquinoline alkaloid
GO:0071320: cellular response to cAMP
GO:0071363: cellular response to growth factor stimulus
GO:0071372: cellular response to follicle-stimulating hormone stimulus
GO:0071383: cellular response to steroid hormone stimulus
GO:0071455: cellular response to hyperoxia
GO:0071456: cellular response to hypoxia
GO:0071480: cellular response to gamma radiation
GO:0071504: cellular response to heparin
GO:0071506: cellular response to mycophenolic acid
GO:0071873: response to norepinephrine stimulus
GO:0072110: glomerular mesangial cell proliferation
GO:0072303: positive regulation of glomerular metanephric mesangial cell proliferation
GO:0090090: negative regulation of canonical Wnt receptor signaling pathway
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005515: protein binding
GO:0000976: transcription regulatory region sequence-specific DNA binding
GO:0000979: RNA polymerase II core promoter sequence-specific DNA binding
GO:0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677: DNA binding
GO:0003690: double-stranded DNA binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0046872: metal ion binding
GO:0008134: transcription factor binding
GO:0035035: histone acetyltransferase binding
GO:0043565: sequence-specific DNA binding
KEGG pathways 5020: Prion diseases

PubMed abstracts associated with EGR1

PMID Title Tumor Value
7585551 Egr-1 negatively regulates human tumor cell growth via the DNA-binding domain. no no
21283769 Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activator activity via up-regulation of EGR1. yes no
title all all