General Information
Gene ID | 1958 |
---|---|
Gene Symbol | EGR1 |
Gene Name | early growth response 1 |
Gene Type | protein-coding |
Cytoband | 5q31.1 |
Ensembl ID | ENSG00000120738 |
#miR regulators | 10 |
Omim ID | 128990 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001975: response to amphetamine GO:0006366: transcription from RNA polymerase II promoter GO:0007611: learning or memory GO:0007623: circadian rhythm GO:0009749: response to glucose stimulus GO:0045893: positive regulation of transcription, DNA-dependent GO:0019221: cytokine-mediated signaling pathway GO:0071260: cellular response to mechanical stimulus GO:0030217: T cell differentiation GO:0030509: BMP signaling pathway GO:0031667: response to nutrient levels GO:0032869: cellular response to insulin stimulus GO:0033233: regulation of protein sumoylation GO:0034465: response to carbon monoxide GO:0035690: cellular response to drug GO:0035914: skeletal muscle cell differentiation GO:0042220: response to cocaine GO:0043525: positive regulation of neuron apoptotic process GO:0045471: response to ethanol GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048169: regulation of long-term neuronal synaptic plasticity GO:0048709: oligodendrocyte differentiation GO:0051602: response to electrical stimulus GO:0060291: long-term synaptic potentiation GO:0060337: type I interferon-mediated signaling pathway GO:0070498: interleukin-1-mediated signaling pathway GO:0071236: cellular response to antibiotic GO:0071317: cellular response to isoquinoline alkaloid GO:0071320: cellular response to cAMP GO:0071363: cellular response to growth factor stimulus GO:0071372: cellular response to follicle-stimulating hormone stimulus GO:0071383: cellular response to steroid hormone stimulus GO:0071455: cellular response to hyperoxia GO:0071456: cellular response to hypoxia GO:0071480: cellular response to gamma radiation GO:0071504: cellular response to heparin GO:0071506: cellular response to mycophenolic acid GO:0071873: response to norepinephrine stimulus GO:0072110: glomerular mesangial cell proliferation GO:0072303: positive regulation of glomerular metanephric mesangial cell proliferation GO:0090090: negative regulation of canonical Wnt receptor signaling pathway GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005515: protein binding GO:0000976: transcription regulatory region sequence-specific DNA binding GO:0000979: RNA polymerase II core promoter sequence-specific DNA binding GO:0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription GO:0003677: DNA binding GO:0003690: double-stranded DNA binding GO:0003700: sequence-specific DNA binding transcription factor activity GO:0046872: metal ion binding GO:0008134: transcription factor binding GO:0035035: histone acetyltransferase binding GO:0043565: sequence-specific DNA binding |
KEGG pathways |
5020: Prion diseases |
PMID | Title | Tumor | Value |
---|---|---|---|
7585551 | Egr-1 negatively regulates human tumor cell growth via the DNA-binding domain. | no | no |
21283769 | Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activator activity via up-regulation of EGR1. | yes | no |
title | all | all |