General Information
| Gene ID | 1965 |
|---|---|
| Gene Symbol | EIF2S1 |
| Gene Name | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
| Gene Type | protein-coding |
| Cytoband | 14q23.3 |
| Ensembl ID | ENSG00000134001 |
| #miR regulators | 17 |
| Omim ID | 603907 |
| Gene ontology |
GO:0006412: translation GO:0006413: translational initiation GO:0006987: activation of signaling protein activity involved in unfolded protein response GO:0010467: gene expression GO:0030968: endoplasmic reticulum unfolded protein response GO:0043558: regulation of translational initiation in response to stress GO:0044267: cellular protein metabolic process GO:0046777: protein autophosphorylation GO:0005829: cytosol GO:0005634: nucleus GO:0005844: polysome GO:0005850: eukaryotic translation initiation factor 2 complex GO:0005851: eukaryotic translation initiation factor 2B complex GO:0010494: cytoplasmic stress granule GO:0005515: protein binding GO:0003743: translation initiation factor activity GO:0043022: ribosome binding |
| KEGG pathways |
3013: RNA transport 4141: Protein processing in endoplasmic reticulum 5160: Hepatitis C |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 15625311 | Okadaic acid induces apoptosis through double-stranded RNA-dependent protein kinase/eukaryotic initiation factor-2alpha pathway in human osteoblastic MG63 cells. | no | no |
| title | all | all |