General Information
Gene ID | 1969 |
---|---|
Gene Symbol | EPHA2 |
Gene Name | EPH receptor A2 |
Gene Type | protein-coding |
Cytoband | 1p36 |
Ensembl ID | ENSG00000142627 |
#miR regulators | 5 |
Omim ID | 116600 176946 |
Gene ontology |
GO:0001501: skeletal system development GO:0001525: angiogenesis GO:0001570: vasculogenesis GO:0001649: osteoblast differentiation GO:0007155: cell adhesion GO:0007275: multicellular organismal development GO:0008630: intrinsic apoptotic signaling pathway in response to DNA damage GO:0010591: regulation of lamellipodium assembly GO:0014028: notochord formation GO:0021915: neural tube development GO:0030182: neuron differentiation GO:0030216: keratinocyte differentiation GO:0030316: osteoclast differentiation GO:0032863: activation of Rac GTPase activity GO:0033598: mammary gland epithelial cell proliferation GO:0033628: regulation of cell adhesion mediated by integrin GO:0036342: post-anal tail morphogenesis GO:0043491: protein kinase B signaling cascade GO:0043535: regulation of blood vessel endothelial cell migration GO:0045765: regulation of angiogenesis GO:0046849: bone remodeling GO:0048013: ephrin receptor signaling pathway GO:0048320: axial mesoderm formation GO:0070848: response to growth factor stimulus GO:0051898: negative regulation of protein kinase B signaling cascade GO:0060035: notochord cell development GO:0060326: cell chemotaxis GO:0060444: branching involved in mammary gland duct morphogenesis GO:0070309: lens fiber cell morphogenesis GO:0070372: regulation of ERK1 and ERK2 cascade GO:0090004: positive regulation of establishment of protein localization to plasma membrane GO:0005886: plasma membrane GO:0005887: integral to plasma membrane GO:0005925: focal adhesion GO:0031256: leading edge membrane GO:0031258: lamellipodium membrane GO:0032587: ruffle membrane GO:0005515: protein binding GO:0004714: transmembrane receptor protein tyrosine kinase activity GO:0005003: ephrin receptor activity GO:0005524: ATP binding |
KEGG pathways |
4360: Axon guidance |
PMID | Title | Tumor | Value |
---|---|---|---|
21166698 | De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway. | no | no |
title | all | all |