Results for FLCN

General Information

Gene ID 201163
Gene Symbol FLCN
Gene Name folliculin
Gene Type protein-coding
Cytoband 17p11.2
Ensembl ID ENSG00000154803
#miR regulators 8
Omim ID 114500 135150 144700 173600 607273
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001701: in utero embryonic development
GO:0001932: regulation of protein phosphorylation
GO:0001934: positive regulation of protein phosphorylation
GO:0006950: response to stress
GO:0007043: cell-cell junction assembly
GO:0010628: positive regulation of gene expression
GO:0010629: negative regulation of gene expression
GO:0010823: negative regulation of mitochondrion organization
GO:0030097: hemopoiesis
GO:0030308: negative regulation of cell growth
GO:0030336: negative regulation of cell migration
GO:0030511: positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031929: TOR signaling cascade
GO:0032006: regulation of TOR signaling cascade
GO:0032007: negative regulation of TOR signaling cascade
GO:0032008: positive regulation of TOR signaling cascade
GO:0032465: regulation of cytokinesis
GO:0035024: negative regulation of Rho protein signal transduction
GO:0035065: regulation of histone acetylation
GO:0043065: positive regulation of apoptotic process
GO:0045785: positive regulation of cell adhesion
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0051898: negative regulation of protein kinase B signaling cascade
GO:0070373: negative regulation of ERK1 and ERK2 cascade
GO:1900181: negative regulation of protein localization to nucleus
GO:1901723: negative regulation of cell proliferation involved in kidney development
GO:1901856: negative regulation of cellular respiration
GO:1901859: negative regulation of mitochondrial DNA metabolic process
GO:1901862: negative regulation of muscle tissue development
GO:1901874: negative regulation of post-translational protein modification
GO:2000506: negative regulation of energy homeostasis
GO:2000973: regulation of pro-B cell differentiation
GO:2001170: negative regulation of ATP biosynthetic process
GO:0005886: plasma membrane
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0030496: midbody
GO:0044291: cell-cell contact zone
GO:0005515: protein binding
GO:0032403: protein complex binding
KEGG pathways 5211: Renal cell carcinoma

PubMed abstracts associated with FLCN

PMID Title Tumor Value
17317953 Loss of TP53 in sarcomas with 17p12 to approximately p11 gain. A fine-resolution oligonucleotide array comparative genomic hybridization study. yes no
title all all