General Information
Gene ID | 201163 |
---|---|
Gene Symbol | FLCN |
Gene Name | folliculin |
Gene Type | protein-coding |
Cytoband | 17p11.2 |
Ensembl ID | ENSG00000154803 |
#miR regulators | 8 |
Omim ID | 114500 135150 144700 173600 607273 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001701: in utero embryonic development GO:0001932: regulation of protein phosphorylation GO:0001934: positive regulation of protein phosphorylation GO:0006950: response to stress GO:0007043: cell-cell junction assembly GO:0010628: positive regulation of gene expression GO:0010629: negative regulation of gene expression GO:0010823: negative regulation of mitochondrion organization GO:0030097: hemopoiesis GO:0030308: negative regulation of cell growth GO:0030336: negative regulation of cell migration GO:0030511: positive regulation of transforming growth factor beta receptor signaling pathway GO:0031929: TOR signaling cascade GO:0032006: regulation of TOR signaling cascade GO:0032007: negative regulation of TOR signaling cascade GO:0032008: positive regulation of TOR signaling cascade GO:0032465: regulation of cytokinesis GO:0035024: negative regulation of Rho protein signal transduction GO:0035065: regulation of histone acetylation GO:0043065: positive regulation of apoptotic process GO:0045785: positive regulation of cell adhesion GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0051898: negative regulation of protein kinase B signaling cascade GO:0070373: negative regulation of ERK1 and ERK2 cascade GO:1900181: negative regulation of protein localization to nucleus GO:1901723: negative regulation of cell proliferation involved in kidney development GO:1901856: negative regulation of cellular respiration GO:1901859: negative regulation of mitochondrial DNA metabolic process GO:1901862: negative regulation of muscle tissue development GO:1901874: negative regulation of post-translational protein modification GO:2000506: negative regulation of energy homeostasis GO:2000973: regulation of pro-B cell differentiation GO:2001170: negative regulation of ATP biosynthetic process GO:0005886: plasma membrane GO:0005634: nucleus GO:0005737: cytoplasm GO:0030496: midbody GO:0044291: cell-cell contact zone GO:0005515: protein binding GO:0032403: protein complex binding |
KEGG pathways |
5211: Renal cell carcinoma |
PMID | Title | Tumor | Value |
---|---|---|---|
17317953 | Loss of TP53 in sarcomas with 17p12 to approximately p11 gain. A fine-resolution oligonucleotide array comparative genomic hybridization study. | yes | no |
title | all | all |