General Information
| Gene ID | 2021 |
|---|---|
| Gene Symbol | ENDOG |
| Gene Name | endonuclease G |
| Gene Type | protein-coding |
| Cytoband | 9q34.1 |
| Ensembl ID | ENSG00000167136 |
| #miR regulators | --- |
| Omim ID | 600440 |
| Gene ontology |
GO:0001701: in utero embryonic development GO:0006309: apoptotic DNA fragmentation GO:0046677: response to antibiotic GO:0034612: response to tumor necrosis factor GO:0043065: positive regulation of apoptotic process GO:0005739: mitochondrion GO:0003676: nucleic acid binding GO:0004519: endonuclease activity GO:0046872: metal ion binding |
| KEGG pathways |
4210: Apoptosis |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 17356895 | Caspase-independent death of human osteosarcoma cells by flavonoids is driven by p53-mediated mitochondrial stress and nuclear translocation of AIF and endonuclease G. | no | no |
| 21573491 | Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. | no | no |
| title | all | all |