General Information
Gene ID | 2022 |
---|---|
Gene Symbol | ENG |
Gene Name | endoglin |
Gene Type | protein-coding |
Cytoband | 9q34.11 |
Ensembl ID | ENSG00000106991 |
#miR regulators | --- |
Omim ID | 131195 187300 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001300: chronological cell aging GO:0001569: patterning of blood vessels GO:0001570: vasculogenesis GO:0001666: response to hypoxia GO:0001934: positive regulation of protein phosphorylation GO:0001937: negative regulation of endothelial cell proliferation GO:0001947: heart looping GO:0003084: positive regulation of systemic arterial blood pressure GO:0003273: cell migration involved in endocardial cushion formation GO:0007155: cell adhesion GO:0006355: regulation of transcription, DNA-dependent GO:0007179: transforming growth factor beta receptor signaling pathway GO:0010862: positive regulation of pathway-restricted SMAD protein phosphorylation GO:0016477: cell migration GO:0017015: regulation of transforming growth factor beta receptor signaling pathway GO:0022009: central nervous system vasculogenesis GO:0022617: extracellular matrix disassembly GO:0030155: regulation of cell adhesion GO:0030336: negative regulation of cell migration GO:0030509: BMP signaling pathway GO:0030512: negative regulation of transforming growth factor beta receptor signaling pathway GO:0030513: positive regulation of BMP signaling pathway GO:0031953: negative regulation of protein autophosphorylation GO:0042060: wound healing GO:0042127: regulation of cell proliferation GO:0042325: regulation of phosphorylation GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048745: smooth muscle tissue development GO:0048844: artery morphogenesis GO:0048845: venous blood vessel morphogenesis GO:0048870: cell motility GO:0051001: negative regulation of nitric-oxide synthase activity GO:0060326: cell chemotaxis GO:0060394: negative regulation of pathway-restricted SMAD protein phosphorylation GO:0070483: detection of hypoxia GO:0005615: extracellular space GO:0005634: nucleus GO:0005737: cytoplasm GO:0009897: external side of plasma membrane GO:0009986: cell surface GO:0070022: transforming growth factor beta receptor homodimeric complex GO:0072563: endothelial microparticle GO:0005515: protein binding GO:0004888: transmembrane signaling receptor activity GO:0005024: transforming growth factor beta-activated receptor activity GO:0005072: transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005114: type II transforming growth factor beta receptor binding GO:0005534: galactose binding GO:0005539: glycosaminoglycan binding GO:0050431: transforming growth factor beta binding GO:0034713: type I transforming growth factor beta receptor binding GO:0042803: protein homodimerization activity GO:0048185: activin binding |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
19584295 | Expression of an exogenous human Oct-4 promoter identifies tumor-initiating cells in osteosarcoma. | no | no |
title | all | all |