General Information
Gene ID | 2033 |
---|---|
Gene Symbol | EP300 |
Gene Name | E1A binding protein p300 |
Gene Type | protein-coding |
Cytoband | 22q13.2 |
Ensembl ID | ENSG00000100393 |
#miR regulators | 4 |
Omim ID | 114500 180849 602700 613684 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001666: response to hypoxia GO:0001756: somitogenesis GO:0006915: apoptotic process GO:0006351: transcription, DNA-dependent GO:0006355: regulation of transcription, DNA-dependent GO:0007049: cell cycle GO:0007219: Notch signaling pathway GO:0009887: organ morphogenesis GO:0007399: nervous system development GO:0007507: heart development GO:0007519: skeletal muscle tissue development GO:0018076: N-terminal peptidyl-lysine acetylation GO:0018393: internal peptidyl-lysine acetylation GO:0019048: modulation by virus of host morphology or physiology GO:0030324: lung development GO:0032092: positive regulation of protein binding GO:0032481: positive regulation of type I interferon production GO:0042771: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0043627: response to estrogen stimulus GO:0043923: positive regulation by host of viral transcription GO:0043967: histone H4 acetylation GO:0045087: innate immune response GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity GO:0060765: regulation of androgen receptor signaling pathway GO:0061418: regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0071456: cellular response to hypoxia GO:0000123: histone acetyltransferase complex GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005667: transcription factor complex GO:0005515: protein binding GO:0001047: core promoter binding GO:0001102: RNA polymerase II activating transcription factor binding GO:0002039: p53 binding GO:0003677: DNA binding GO:0003682: chromatin binding GO:0003713: transcription coactivator activity GO:0004402: histone acetyltransferase activity GO:0004468: lysine N-acetyltransferase activity GO:0008013: beta-catenin binding GO:0008134: transcription factor binding GO:0008270: zinc ion binding GO:0016407: acetyltransferase activity GO:0016746: transferase activity, transferring acyl groups GO:0031490: chromatin DNA binding GO:0033613: activating transcription factor binding GO:0050681: androgen receptor binding |
KEGG pathways |
4110: Cell cycle 4310: Wnt signaling pathway 4330: Notch signaling pathway 4350: TGF-beta signaling pathway 4520: Adherens junction 4630: Jak-STAT signaling pathway 4720: Long-term potentiation 4916: Melanogenesis 5016: Huntington's disease 5200: Pathways in cancer 5211: Renal cell carcinoma 5215: Prostate cancer |
PMID | Title | Tumor | Value |
---|---|---|---|
12789260 | Triggering of p73-dependent apoptosis in osteosarcoma is under the control of E2Fs-pRb2/p130 complexes. | no | no |
16734381 | Sp1 family of transcription factors regulates the human alpha2 (XI) collagen gene (COL11A2) in Saos-2 osteoblastic cells. | no | no |
title | all | all |