Results for EP300

General Information

Gene ID 2033
Gene Symbol EP300
Gene Name E1A binding protein p300
Gene Type protein-coding
Cytoband 22q13.2
Ensembl ID ENSG00000100393
#miR regulators 4
Omim ID 114500 180849 602700 613684
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001666: response to hypoxia
GO:0001756: somitogenesis
GO:0006915: apoptotic process
GO:0006351: transcription, DNA-dependent
GO:0006355: regulation of transcription, DNA-dependent
GO:0007049: cell cycle
GO:0007219: Notch signaling pathway
GO:0009887: organ morphogenesis
GO:0007399: nervous system development
GO:0007507: heart development
GO:0007519: skeletal muscle tissue development
GO:0018076: N-terminal peptidyl-lysine acetylation
GO:0018393: internal peptidyl-lysine acetylation
GO:0019048: modulation by virus of host morphology or physiology
GO:0030324: lung development
GO:0032092: positive regulation of protein binding
GO:0032481: positive regulation of type I interferon production
GO:0042771: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043627: response to estrogen stimulus
GO:0043923: positive regulation by host of viral transcription
GO:0043967: histone H4 acetylation
GO:0045087: innate immune response
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060765: regulation of androgen receptor signaling pathway
GO:0061418: regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456: cellular response to hypoxia
GO:0000123: histone acetyltransferase complex
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005667: transcription factor complex
GO:0005515: protein binding
GO:0001047: core promoter binding
GO:0001102: RNA polymerase II activating transcription factor binding
GO:0002039: p53 binding
GO:0003677: DNA binding
GO:0003682: chromatin binding
GO:0003713: transcription coactivator activity
GO:0004402: histone acetyltransferase activity
GO:0004468: lysine N-acetyltransferase activity
GO:0008013: beta-catenin binding
GO:0008134: transcription factor binding
GO:0008270: zinc ion binding
GO:0016407: acetyltransferase activity
GO:0016746: transferase activity, transferring acyl groups
GO:0031490: chromatin DNA binding
GO:0033613: activating transcription factor binding
GO:0050681: androgen receptor binding
KEGG pathways 4110: Cell cycle
4310: Wnt signaling pathway
4330: Notch signaling pathway
4350: TGF-beta signaling pathway
4520: Adherens junction
4630: Jak-STAT signaling pathway
4720: Long-term potentiation
4916: Melanogenesis
5016: Huntington's disease
5200: Pathways in cancer
5211: Renal cell carcinoma
5215: Prostate cancer

PubMed abstracts associated with EP300

PMID Title Tumor Value
12789260 Triggering of p73-dependent apoptosis in osteosarcoma is under the control of E2Fs-pRb2/p130 complexes. no no
16734381 Sp1 family of transcription factors regulates the human alpha2 (XI) collagen gene (COL11A2) in Saos-2 osteoblastic cells. no no
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