General Information
Gene ID | 2034 |
---|---|
Gene Symbol | EPAS1 |
Gene Name | endothelial PAS domain protein 1 |
Gene Type | protein-coding |
Cytoband | 2p21-p16 |
Ensembl ID | ENSG00000116016 |
#miR regulators | 8 |
Omim ID | 603349 611783 |
Gene ontology |
GO:0001525: angiogenesis GO:0001666: response to hypoxia GO:0001892: embryonic placenta development GO:0001974: blood vessel remodeling GO:0002027: regulation of heart rate GO:0006366: transcription from RNA polymerase II promoter GO:0007165: signal transduction GO:0007005: mitochondrion organization GO:0007601: visual perception GO:0030218: erythrocyte differentiation GO:0030324: lung development GO:0042415: norepinephrine metabolic process GO:0043129: surfactant homeostasis GO:0043619: regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048469: cell maturation GO:0048625: myoblast fate commitment GO:0061418: regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0071456: cellular response to hypoxia GO:0005829: cytosol GO:0005654: nucleoplasm GO:0005667: transcription factor complex GO:0005515: protein binding GO:0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription GO:0003677: DNA binding GO:0004871: signal transducer activity GO:0008134: transcription factor binding GO:0035035: histone acetyltransferase binding GO:0043565: sequence-specific DNA binding GO:0046982: protein heterodimerization activity |
KEGG pathways |
5200: Pathways in cancer 5211: Renal cell carcinoma |
PMID | Title | Tumor | Value |
---|---|---|---|
20637078 | Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor. | no | no |
22544557 | Expression and stability of hypoxia inducible factor 1α in osteosarcoma. | yes | no |
title | all | all |