Results for EPAS1

General Information

Gene ID 2034
Gene Symbol EPAS1
Gene Name endothelial PAS domain protein 1
Gene Type protein-coding
Cytoband 2p21-p16
Ensembl ID ENSG00000116016
#miR regulators 8
Omim ID 603349 611783
Gene ontology GO:0001525: angiogenesis
GO:0001666: response to hypoxia
GO:0001892: embryonic placenta development
GO:0001974: blood vessel remodeling
GO:0002027: regulation of heart rate
GO:0006366: transcription from RNA polymerase II promoter
GO:0007165: signal transduction
GO:0007005: mitochondrion organization
GO:0007601: visual perception
GO:0030218: erythrocyte differentiation
GO:0030324: lung development
GO:0042415: norepinephrine metabolic process
GO:0043129: surfactant homeostasis
GO:0043619: regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048469: cell maturation
GO:0048625: myoblast fate commitment
GO:0061418: regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456: cellular response to hypoxia
GO:0005829: cytosol
GO:0005654: nucleoplasm
GO:0005667: transcription factor complex
GO:0005515: protein binding
GO:0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677: DNA binding
GO:0004871: signal transducer activity
GO:0008134: transcription factor binding
GO:0035035: histone acetyltransferase binding
GO:0043565: sequence-specific DNA binding
GO:0046982: protein heterodimerization activity
KEGG pathways 5200: Pathways in cancer
5211: Renal cell carcinoma

PubMed abstracts associated with EPAS1

PMID Title Tumor Value
20637078 Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor. no no
22544557 Expression and stability of hypoxia inducible factor 1? in osteosarcoma. yes no
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