General Information
Gene ID | 2065 |
---|---|
Gene Symbol | ERBB3 |
Gene Name | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
Gene Type | protein-coding |
Cytoband | 12q13 |
Ensembl ID | ENSG00000065361 |
#miR regulators | 19 |
Omim ID | 190151 607598 |
Gene ontology |
GO:0003197: endocardial cushion development GO:0007165: signal transduction GO:0007169: transmembrane receptor protein tyrosine kinase signaling pathway GO:0007162: negative regulation of cell adhesion GO:0007173: epidermal growth factor receptor signaling pathway GO:0007422: peripheral nervous system development GO:0007507: heart development GO:0008543: fibroblast growth factor receptor signaling pathway GO:0009968: negative regulation of signal transduction GO:0014037: Schwann cell differentiation GO:0014065: phosphatidylinositol 3-kinase cascade GO:0014068: positive regulation of phosphatidylinositol 3-kinase cascade GO:0048015: phosphatidylinositol-mediated signaling GO:0021545: cranial nerve development GO:0038095: Fc-epsilon receptor signaling pathway GO:0042060: wound healing GO:0042127: regulation of cell proliferation GO:0043524: negative regulation of neuron apoptotic process GO:0045087: innate immune response GO:0048011: neurotrophin TRK receptor signaling pathway GO:0051048: negative regulation of secretion GO:0051402: neuron apoptotic process GO:0061098: positive regulation of protein tyrosine kinase activity GO:0097192: extrinsic apoptotic signaling pathway in absence of ligand GO:0005886: plasma membrane GO:0005887: integral to plasma membrane GO:0005615: extracellular space GO:0016323: basolateral plasma membrane GO:0016324: apical plasma membrane GO:0016328: lateral plasma membrane GO:0043235: receptor complex GO:0005515: protein binding GO:0004888: transmembrane signaling receptor activity GO:0019838: growth factor binding GO:0005524: ATP binding GO:0042802: identical protein binding GO:0030296: protein tyrosine kinase activator activity GO:0042803: protein homodimerization activity GO:0046982: protein heterodimerization activity |
KEGG pathways |
4012: ErbB signaling pathway 4020: Calcium signaling pathway 4144: Endocytosis |
PMID | Title | Tumor | Value |
---|---|---|---|
23530647 | Induction of cell cycle arrest and apoptosis in human osteosarcoma U-2 OS cells by Solanum lyratum extracts. | yes | no |
title | all | all |