Results for ERBB3

General Information

Gene ID 2065
Gene Symbol ERBB3
Gene Name v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Gene Type protein-coding
Cytoband 12q13
Ensembl ID ENSG00000065361
#miR regulators 19
Omim ID 190151 607598
Gene ontology GO:0003197: endocardial cushion development
GO:0007165: signal transduction
GO:0007169: transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007162: negative regulation of cell adhesion
GO:0007173: epidermal growth factor receptor signaling pathway
GO:0007422: peripheral nervous system development
GO:0007507: heart development
GO:0008543: fibroblast growth factor receptor signaling pathway
GO:0009968: negative regulation of signal transduction
GO:0014037: Schwann cell differentiation
GO:0014065: phosphatidylinositol 3-kinase cascade
GO:0014068: positive regulation of phosphatidylinositol 3-kinase cascade
GO:0048015: phosphatidylinositol-mediated signaling
GO:0021545: cranial nerve development
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0042060: wound healing
GO:0042127: regulation of cell proliferation
GO:0043524: negative regulation of neuron apoptotic process
GO:0045087: innate immune response
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0051048: negative regulation of secretion
GO:0051402: neuron apoptotic process
GO:0061098: positive regulation of protein tyrosine kinase activity
GO:0097192: extrinsic apoptotic signaling pathway in absence of ligand
GO:0005886: plasma membrane
GO:0005887: integral to plasma membrane
GO:0005615: extracellular space
GO:0016323: basolateral plasma membrane
GO:0016324: apical plasma membrane
GO:0016328: lateral plasma membrane
GO:0043235: receptor complex
GO:0005515: protein binding
GO:0004888: transmembrane signaling receptor activity
GO:0019838: growth factor binding
GO:0005524: ATP binding
GO:0042802: identical protein binding
GO:0030296: protein tyrosine kinase activator activity
GO:0042803: protein homodimerization activity
GO:0046982: protein heterodimerization activity
KEGG pathways 4012: ErbB signaling pathway
4020: Calcium signaling pathway
4144: Endocytosis

PubMed abstracts associated with ERBB3

PMID Title Tumor Value
23530647 Induction of cell cycle arrest and apoptosis in human osteosarcoma U-2 OS cells by Solanum lyratum extracts. yes no
title all all